Cefamandole nafate
Cefamandole nafate (CAS 42540-40-9) is a potent antibacterial agent with the molecular formula C19H17N6O6S2Na and a molecular weight of 512.49 g/mol. As a sodium salt, it functions by interfering with bacterial cell wall synthesis, making it valuable in microbiological research for studying penicillin-binding proteins (PBPs) and their roles in bacterial growth and resistance. This compound is supplied by Tech Serve Solutions for laboratory and research applications.
- IUPAC
- Cefamandole formate sodium salt
Antibacterial Research
Cefamandole nafate serves as a critical tool in research laboratories to investigate the mechanisms of antibacterial action, specifically focusing on the inhibition of penicillin-binding proteins (PBPs) like PBP 2A. This aids in understanding bacterial cell wall synthesis and developing strategies against antibiotic resistance.
Microbiological Studies
Utilised for its specific mode of action, this compound is employed in studies examining the expression and inhibition of PBPs. It helps researchers elucidate the intricate processes of bacterial cell wall construction and the impact of targeted interventions.
Drug Discovery and Development
The compound can be instrumental in the early stages of drug discovery, providing a reference standard or research probe for identifying and characterising novel antibacterial agents with similar mechanisms of action.
| Molecular weight | 512.49 |
|---|---|
| Linear formula | C19H17N6O6S2Na |
| Assay | ~95% |
| Application | Cefamandole is used to study the effects of expression and inhibition of PBP 2A and other penicillin-binding proteins (PDPs) on bacterial cell wall mucopeptide synthesis. |
Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38-42/43 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cefamandole nafate used for?
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Cefamandole nafate is used in research to study the expression and inhibition of penicillin-binding proteins (PBPs) and their effects on bacterial cell wall synthesis. It is an antibacterial agent that interferes with these crucial bacterial processes.
What are the CAS number and formula for Cefamandole nafate?
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The CAS number for Cefamandole nafate is 42540-40-9, and its molecular formula is C19H17N6O6S2Na.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cefamandole nafate with an assay of approximately 95%. This compound is typically considered a research or technical grade chemical, and TSS does not represent it as USP, BP, or EP grade.
How should Cefamandole nafate be handled safely?
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Cefamandole nafate is classified with Danger signal word and carries hazards including skin and eye irritation, respiratory irritation, and potential skin sensitisation (H315, H319, H335, H317). It can also cause respiratory irritation upon inhalation (H334). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shield, and gloves, should be used. Ensure good ventilation and avoid breathing dust.
Can Tech Serve Solutions export Cefamandole nafate?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and laboratory reagents, including Cefamandole nafate.
How can I request a quote or sample for Cefamandole nafate?
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To request a quote or sample for Cefamandole nafate, please contact our sales team through the website or by phone, providing the product name, CAS number, and desired quantity.
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