3-Chloro-4′-fluoropropiophenone
3-Chloro-4′-fluoropropiophenone (CAS: 347-93-3) is a halogenated propiophenone derivative with the linear formula C<sub>6</sub>H<sub>4</sub>COCH<sub>2</sub>CH<sub>2</sub>Cl. This organic compound serves as a versatile building block in chemical synthesis, particularly for introducing fluorinated aryl moieties into more complex molecular structures. Its utility spans various research and development applications within organic chemistry and materials science.
Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of diverse organic compounds. Its reactive chloro and fluoro substituents, along with the propiophenone core, allow for various chemical transformations.
Pharmaceutical Research
Utilised in the development of novel pharmaceutical candidates. The presence of a fluorine atom can modulate a molecule's metabolic stability, lipophilicity, and binding affinity.
Materials Science
Can be employed in the synthesis of specialised polymers or functional materials where fluorinated aromatic units are desired for specific properties.
Agrochemical Development
Acts as a building block for the creation of new agrochemical agents, leveraging its structural features for potential bioactivity.
| Molecular weight | 186.61 |
|---|---|
| Linear formula | FC6H4COCH2CH2Cl |
| Assay | 98% |
| Melting point | 47-49 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | 92 °C / 197.6 °F |
|---|---|
| Transport (UN / ADR) | UN 1325 4.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-52/53 |
| Safety statements (S) | 26-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-4′-fluoropropiophenone used for?
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3-Chloro-4′-fluoropropiophenone is primarily used as an intermediate in organic synthesis, including pharmaceutical research, materials science, and agrochemical development.
What is the CAS number and linear formula for 3-Chloro-4′-fluoropropiophenone?
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The CAS number is 347-93-3 and the linear formula is C<sub>6</sub>H<sub>4</sub>COCH<sub>2</sub>CH<sub>2</sub>Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Chloro-4′-fluoropropiophenone with an assay of 98%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and technical applications.
What are the safety considerations when handling 3-Chloro-4′-fluoropropiophenone?
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3-Chloro-4′-fluoropropiophenone is classified as harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area.
Is 3-Chloro-4′-fluoropropiophenone packed and shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter and can arrange for the packing and shipment of 3-Chloro-4′-fluoropropiophenone worldwide.
How can I request a quote or sample for 3-Chloro-4′-fluoropropiophenone?
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To request a quote or sample, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels.
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