3-Chloro-4-pyridineboronic acid pinacol ester
3-Chloro-4-pyridineboronic acid pinacol ester (CAS 458532-90-6), with the molecular formula C11H15BClNO2 and molecular weight 239.51 g/mol, is a valuable organoboron compound. It serves as a key building block in organic synthesis, particularly in cross-coupling reactions for the construction of complex molecules. Its pyridine and boronate ester functionalities make it useful in medicinal chemistry and materials science research.
Suzuki-Miyaura Cross-Coupling Reactions
This pinacol ester is widely employed as a coupling partner in Suzuki-Miyaura reactions, enabling the formation of carbon-carbon bonds with aryl or vinyl halides. It is instrumental in the synthesis of substituted pyridines, which are prevalent in pharmaceuticals and agrochemicals.
Medicinal Chemistry Research
The compound's structure, featuring a chlorinated pyridine ring, makes it a useful intermediate for developing novel drug candidates. It allows for the introduction of specific heterocyclic motifs into biologically active molecules.
Materials Science
3-Chloro-4-pyridineboronic acid pinacol ester can be incorporated into the synthesis of functional materials, such as organic light-emitting diodes (OLEDs) or polymers, where its electronic and structural properties are advantageous.
Organic Synthesis Intermediate
As a versatile building block, it facilitates the synthesis of various complex organic structures through diverse synthetic transformations beyond cross-coupling, contributing to academic and industrial research.
| Molecular weight | 239.51 |
|---|---|
| Empirical formula | C11H15BClNO2 |
| Assay | 97% |
| Melting point | 86-90 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-4-pyridineboronic acid pinacol ester used for?
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This compound is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for creating carbon-carbon bonds. It is valuable in medicinal chemistry for developing new drug candidates and in materials science for synthesizing functional materials.
What is the CAS number and molecular formula for 3-Chloro-4-pyridineboronic acid pinacol ester?
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The CAS number is 458532-90-6, and the molecular formula is C11H15BClNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the main hazards associated with handling this chemical?
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This compound is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves, should be used.
How is 3-Chloro-4-pyridineboronic acid pinacol ester packed and shipped?
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We ensure secure packaging suitable for international export of chemicals, adhering to all relevant shipping regulations. Please contact us for specific details on shipping and export services.
How can I request a sample or quote for this product?
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To request a sample or obtain a quotation, please use the contact form on our website or email our sales department, providing your specific requirements and shipping details.
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