(1,3-Dioxan-2-ylethyl)magnesium bromide solution

CAS 480438-44-6C6H11BrMgO2Chemical Synthesis

(1,3-Dioxan-2-ylethyl)magnesium bromide solution (CAS 480438-44-6) is an organometallic reagent with the empirical formula C6H11BrMgO2 and a molecular weight of 219.36 g/mol. Supplied as a 0.5 M solution in THF, this compound is primarily utilised in organic synthesis. It plays a key role in Grignard addition-acylation reactions, notably for the preparation of enamides, offering a specific pathway for the introduction of functionalised ethyl groups.

Synonyms: C6H11BrMgO2

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(1,3-Dioxan-2-ylethyl)magnesium bromide solution (C6H11BrMgO2) — chemical structure, CAS 480438-44-6; Chemistry, fine chemical supplied by Tech Serve Solutions

AlkylChemical SynthesisGrignard ReagentsOrganometallic Reagents

01 /Applications

Enamide Synthesis via Grignard Addition-Acylation

This reagent is specifically employed in the Grignard addition-acylation methodology for the synthesis of enamides. It allows for the controlled introduction of the (1,3-dioxan-2-ylethyl) moiety into organic structures.

Organometallic Synthesis

As a Grignard reagent, it participates in nucleophilic addition reactions with various electrophiles, facilitating the formation of new carbon-carbon bonds in complex molecule synthesis.

Chemical Synthesis Reagent

It serves as a versatile building block in general chemical synthesis, enabling the construction of diverse organic molecules in research and development settings.

02 /Properties

Molecular weight	219.36
Empirical formula	C6H11BrMgO2
Boiling point	65 °C
Density	0.951 g/mL at 25 °C
Concentration	0.5 M in THF
Storage temperature	2-8°C
Application	Used in a Grignard addition-acylation method for the preparation enamides.1

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Warning

Hazard statements

H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P281Use personal protective equipment as required
P305IF IN EYES

Transport (UN / ADR)	UN 2924 8(3) / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	19-36/37-40
Safety statements (S)	26-36/37
Supplemental hazards	May form explosive peroxides.

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

480438-44-6

MDL number

MFCD00061518

PubChem substance

24879959

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (1,3-Dioxan-2-ylethyl)magnesium bromide solution used for?

(1,3-Dioxan-2-ylethyl)magnesium bromide solution is used in organic synthesis, specifically for the preparation of enamides via a Grignard addition-acylation method.

What is the CAS number and formula for (1,3-Dioxan-2-ylethyl)magnesium bromide solution?

The CAS number is 480438-44-6 and the empirical formula is C6H11BrMgO2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this compound as a 0.5 M solution in THF. It is typically intended for laboratory research and chemical synthesis and is not supplied as USP, BP, or EP grade.

How should (1,3-Dioxan-2-ylethyl)magnesium bromide solution be handled and stored?

Handle with appropriate personal protective equipment in a well-ventilated area. It is flammable and can form explosive peroxides. Store at 2-8°C. Consult the Safety Data Sheet for comprehensive handling information.