(1,10-Phenanthroline)(trifluoromethyl)copper(I)
(1,10-Phenanthroline)(trifluoromethyl)copper(I), CAS 1300746-79-5, is a sophisticated copper(I) complex featuring a trifluoromethyl ligand coordinated to 1,10-phenanthroline. This stable, single-component reagent is primarily employed as a trifluoromethylating agent. It facilitates the efficient introduction of the trifluoromethyl group onto aryl iodides, even those that are electron-rich, electron-deficient, or sterically hindered, under mild reaction conditions. This makes it a valuable tool in synthetic organic chemistry.
- IUPAC
- Trifluoromethylator®
- Synonyms
- C13H8CuF3N2Trifluoromethylator, A New Arene Trifluoromethylation Reagent: (Phen)Cu-CF3Trifluoromethylator®
Trifluoromethylation of Aryl Iodides
Acts as a highly effective reagent for introducing the trifluoromethyl group onto a diverse range of aryl iodides, including electron-rich, electron-deficient, and sterically hindered substrates.
Broad Substrate Scope
Tolerates various electrophilic functional groups such as aldehydes, nitroarenes, ketones, and esters, allowing for its use in complex molecule synthesis.
Mild Reaction Conditions
Enables trifluoromethylation reactions to proceed efficiently under mild conditions, preserving sensitive functional groups within the target molecules.
| Molecular weight | 312.76 |
|---|---|
| Empirical formula | C13H8CuF3N2 |
| Assay | 90% |
| Storage temperature | 2-8°C |
| Application | Trifluoromethylator, A New Arene Trifluoromethylation Reagent: (Phen)Cu-CF3(Phen)Cu-CF3 is an easily handled, thermally stable, single-component reagent for the trifluoromethylation of aryl iodides. Electron-rich and electron-deficient iodoarenes, as well as sterically-hindered iodoarenes, react in high yield under mild conditions. Electrophilic functional groups, including aldehydes, nitroarenes, ketones and esters are tolerated. The substrate scope of this reagent is broad and the reagent has wide applicability for trifluoromethylation reactions.1 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 21/22-36/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1,10-Phenanthroline)(trifluoromethyl)copper(I) used for?
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(1,10-Phenanthroline)(trifluoromethyl)copper(I) is primarily used as a trifluoromethylating agent for the synthesis of trifluoromethylated aryl compounds, particularly aryl iodides.
What is the CAS number and formula for (1,10-Phenanthroline)(trifluoromethyl)copper(I)?
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The CAS number is 1300746-79-5, and the empirical formula is C13H8CuF3N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at a minimum purity of 90%. This product is not tested or sold as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling this compound?
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This compound is classified as harmful if swallowed and in contact with skin, and causes skin and serious eye irritation. Always handle with appropriate personal protective equipment, including gloves, eye protection, and protective clothing, in a well-ventilated area.
How is (1,10-Phenanthroline)(trifluoromethyl)copper(I) stored and shipped?
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It is recommended to store the compound at 2-8°C. Tech Serve Solutions can export this chemical globally, adhering to all necessary shipping regulations.
How can I request a quote or sample?
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Please contact our sales team or use the online enquiry form on our website to request a quote or a sample of (1,10-Phenanthroline)(trifluoromethyl)copper(I).
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