N-(3-Dimethoxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamide
N-(3-Dimethoxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamide (CAS 824429-53-0; C13H20N2O3; molar mass 252.31 g/mol) is a heterocyclic building block based on a 2-aminopyridine scaffold carrying a pivalamide (2,2-dimethylpropionamide) group and a dimethyl acetal at the 3-position. It is used in chemical synthesis and medicinal chemistry as a protected, functionalised pyridine intermediate. Tech Serve Solutions supplies it as a research-grade reagent for laboratory and process development.
- Synonyms
- N-(3-Dimethoxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamideN-[3-(dimethoxymethyl)pyridin-2-yl]-2,2-dimethylpropanamideN-[3-(dimethoxymethyl)pyridin-2-yl]pivalamide2,2-dimethyl-N-[3-(dimethoxymethyl)pyridin-2-yl]propanamideCAS 824429-53-0
Heterocyclic building block
Serves as a functionalised pyridine intermediate in multi-step organic synthesis, allowing chemists to assemble more complex nitrogen-heterocyclic structures from a defined starting point.
Protected aminopyridine scaffold
The pivalamide (2,2-dimethylpropionamide) group masks the ring 2-amino function, providing a robust protecting and directing group during downstream transformations.
Latent aldehyde via acetal
The 3-dimethoxymethyl (dimethyl acetal) substituent acts as a masked aldehyde that can be revealed under acidic hydrolysis, supporting subsequent condensation or reductive-amination chemistry.
Medicinal and discovery chemistry
Pyridine intermediates of this type are commonly employed in pharmaceutical research and library synthesis. Suitability for any specific target should be confirmed by the user.
Laboratory reference and method development
Used in analytical method development and synthetic route screening where a well-defined, single pyridine building block is required.
| Molecular weight | 252.31 |
|---|---|
| Empirical formula | C13H20N2O3 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(3-Dimethoxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamide used for?
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It is used as a heterocyclic building block and synthetic intermediate. The compound combines a 2-aminopyridine core with a pivalamide protecting group and a dimethyl acetal (masked aldehyde) at the 3-position, making it useful in multi-step organic and medicinal chemistry.
What is the CAS number and molecular formula of N-(3-Dimethoxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamide?
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The CAS number is 824429-53-0 and the empirical formula is C13H20N2O3 (Hill notation), corresponding to a molecular weight of 252.31 g/mol.
What grade and purity does Tech Serve Solutions supply?
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We supply this compound as a research-grade building block for laboratory and process-development use. Unless a specific specification is agreed in writing, it is not represented as USP, BP or EP pharmacopoeia grade. A certificate of analysis with the assay for the dispatched lot is available on request.
How should N-(3-Dimethoxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamide be handled and stored?
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No specific GHS hazard classification is provided in our current data, so it should be handled as a research chemical not for medicinal, household or food use. Use standard laboratory practice: wear suitable gloves and eye protection, work with adequate ventilation, avoid dust and contact, and store in a tightly closed container in a cool, dry place. Acetals are moisture- and acid-sensitive, so protect the material from humidity and acidic conditions.
How is N-(3-Dimethoxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamide packed, shipped and exported?
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The material is packed in appropriately sealed, labelled containers sized to the order, from gram quantities for research to larger lots for scale-up. As a specialist exporter since 1998, Tech Serve Solutions arranges compliant international documentation and shipping, with packaging and transport handled to suit the destination and any applicable regulations.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the product name or CAS 824429-53-0 and your required quantity, purity and destination. We will respond with availability, lead time, specification and a formal quotation, and can provide a certificate of analysis to support your evaluation.
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