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N-(3-Formyl-5-methylpyridin-2-yl)pivalamide

CAS 127446-31-5C12H16N2O2Heterocyclic Building Blocks

N-(3-Formyl-5-methylpyridin-2-yl)pivalamide (CAS 127446-31-5) is a heterocyclic building block with the molecular formula C12H16N2O2 and a molar mass of 220.27 g/mol. It is a functionalised pyridine bearing an aldehyde group and a pivaloyl-protected 2-amino position, used in chemical synthesis and medicinal-chemistry research. Tech Serve Solutions supplies this pyridine intermediate to laboratory, research and fine-chemical customers worldwide.

Synonyms
N-(3-Formyl-5-methylpyridin-2-yl)pivalamideN-(3-formyl-5-methyl-2-pyridinyl)-2,2-dimethylpropanamide2,2-dimethyl-N-(3-formyl-5-methylpyridin-2-yl)propanamidepivaloyl-protected 2-amino-5-methylpyridine-3-carbaldehydeCAS 127446-31-5
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N-(3-Formyl-5-methylpyridin-2-yl)pivalamide (C12H16N2O2) — chemical structure, CAS 127446-31-5; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC12Chemical SynthesisHeterocyclic Building BlocksPyridines
01 /Applications

Heterocyclic building block

Serves as a multifunctional pyridine scaffold in chemical synthesis, providing a reactive aldehyde and a protected amino group on a single methyl-substituted pyridine ring.

Pharmaceutical and medicinal-chemistry intermediate

Used as an intermediate in research-scale synthesis of more complex nitrogen heterocycles and candidate molecules, where the formyl and amide handles enable further elaboration.

Aldehyde-directed transformations

The 3-formyl group supports condensations, reductive aminations and other carbonyl chemistry, allowing the introduction of additional functionality onto the pyridine core.

Pivaloyl-protected amine chemistry

The pivalamide masks the 2-amino position during multi-step sequences and can be removed under appropriate conditions to reveal the free aminopyridine.

Laboratory reagent

Supplied as a reference and synthesis reagent for academic, analytical and industrial research laboratories working with substituted pyridines.

02 /Properties
Molecular weight220.27
Empirical formulaC12H16N2O2
03 /Identifiers & registry
CAS number
127446-31-5
04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is N-(3-Formyl-5-methylpyridin-2-yl)pivalamide used for?

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It is used primarily as a heterocyclic building block and synthetic intermediate. The combination of a reactive 3-formyl (aldehyde) group and a pivaloyl-protected 2-amino group on a 5-methylpyridine ring makes it a versatile scaffold for constructing more complex pyridine derivatives in chemical and medicinal-chemistry research.

What is the CAS number and molecular formula of N-(3-Formyl-5-methylpyridin-2-yl)pivalamide?

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The CAS number is 127446-31-5 and the molecular formula is C12H16N2O2, with a molecular weight of 220.27 g/mol. It is also described as a pivaloyl-protected 2-amino-5-methylpyridine-3-carbaldehyde.

What grade and purity does Tech Serve Solutions supply?

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We supply this compound as a research and synthesis (technical/reagent) grade building block, with specifications confirmed on the certificate of analysis for each batch. We do not represent it as a USP, BP or EP pharmacopoeial grade. Assay, form and detailed specifications can be confirmed against your requirements at the time of enquiry.

How should N-(3-Formyl-5-methylpyridin-2-yl)pivalamide be handled and stored?

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Specific GHS hazard data is not included in our current dataset, so the material should be handled as a research chemical under good laboratory practice: avoid contact with skin, eyes and clothing, avoid dust and vapour, and use appropriate PPE in a well-ventilated area or fume hood. Store in a tightly closed container in a cool, dry place away from incompatible materials, and always consult the accompanying Safety Data Sheet before use.

How is N-(3-Formyl-5-methylpyridin-2-yl)pivalamide packed, shipped and exported?

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It is packed in laboratory- and bulk-appropriate containers with secure inner protection and clear labelling, then shipped with a certificate of analysis and Safety Data Sheet. As a specialist exporter since 1998, Tech Serve Solutions handles the relevant export documentation and arranges compliant international dispatch to research and industrial customers worldwide.

How do I request a sample or quote?

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Contact Tech Serve Solutions with the product name, CAS number 127446-31-5, your required quantity and destination, and we will respond with availability, lead time and a formal quotation. Samples can be discussed for evaluation, subject to availability.

Need N-(3-Formyl-5-methylpyridin-2-yl)pivalamide in a specific grade or volume?