N-(3-Dimethoxymethyl-pyridin-4-yl)-2,2-dimethyl-propionamide
N-(3-Dimethoxymethyl-pyridin-4-yl)-2,2-dimethyl-propionamide (CAS 824429-52-9; C13H20N2O3; molar mass 252.31 g/mol) is a functionalised pyridine building block for organic and pharmaceutical synthesis. It combines a 4-aminopyridine scaffold protected as a pivaloyl (2,2-dimethylpropionamide) amide with a 3-position dimethyl acetal (dimethoxymethyl) group that masks an aldehyde. This dual protection makes it a versatile heterocyclic intermediate for directed functionalisation and downstream multi-step routes. Tech Serve Solutions supplies it to research and manufacturing laboratories worldwide.
- Synonyms
- N-(3-Dimethoxymethyl-pyridin-4-yl)-2,2-dimethyl-propionamideN-[3-(Dimethoxymethyl)pyridin-4-yl]-2,2-dimethylpropanamideN-(3-(Dimethoxymethyl)pyridin-4-yl)pivalamide2,2-Dimethyl-N-[3-(dimethoxymethyl)pyridin-4-yl]propanamideCAS 824429-52-9C13H20N2O3
Pyridine building block for synthesis
Serves as a heterocyclic building block in chemical and pharmaceutical research, providing a substituted 4-aminopyridine core for the assembly of more complex molecules. The pyridine ring offers defined positions for further functionalisation.
Protected aldehyde equivalent
The 3-dimethoxymethyl group is a dimethyl acetal that masks an aldehyde, allowing the carbonyl to be carried through subsequent steps and revealed by mild acid hydrolysis when required. This supports selective, multi-step synthetic sequences.
Amine-protected intermediate
The 2,2-dimethylpropionamide (pivalamide) protects the ring amine and can act as a directing group during metalation or coupling chemistry. It contributes to controlled regioselectivity in elaboration of the pyridine scaffold.
Pharmaceutical intermediate
Used as an intermediate in the preparation of pharmaceutical and other fine-chemical compounds. It is intended for research, development and manufacturing use by qualified laboratories.
Reference and method development
Suitable as a characterised intermediate for analytical method development, process research and route-scouting studies where a defined, well-documented pyridine building block is needed.
| Molecular weight | 252.31 |
|---|---|
| Empirical formula | C13H20N2O3 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(3-Dimethoxymethyl-pyridin-4-yl)-2,2-dimethyl-propionamide used for?
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It is used as a heterocyclic building block and intermediate in organic and pharmaceutical synthesis. The molecule provides a protected 4-aminopyridine bearing a masked aldehyde (dimethyl acetal), which makes it useful for directed functionalisation and multi-step routes to more complex fine chemicals.
What is the CAS number and molecular formula of N-(3-Dimethoxymethyl-pyridin-4-yl)-2,2-dimethyl-propionamide?
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Its CAS number is 824429-52-9 and its empirical (Hill) formula is C13H20N2O3, corresponding to a molecular weight of 252.31 g/mol. It is a pyridine-based building block in the C13 to C15 range.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research/technical-grade synthesis building block for laboratory and manufacturing use. Exact assay is confirmed on the batch certificate of analysis at the time of supply. We do not represent it as USP, BP or EP pharmacopoeial grade; please request current specifications for your application.
What are the safety and handling requirements?
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No specific GHS classification is provided in our current dataset for this material, so it should be treated as a research chemical of undetermined hazard. Handle only with trained personnel using good laboratory practice: wear suitable gloves, eye protection and a lab coat, work with adequate ventilation, avoid dust, skin and eye contact, and keep containers tightly closed. Refer to the Safety Data Sheet supplied with each order before use.
How is N-(3-Dimethoxymethyl-pyridin-4-yl)-2,2-dimethyl-propionamide packed, shipped and exported?
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The product is packed in appropriately sized, well-sealed and labelled containers, from gram quantities for research to larger volumes for development and manufacturing. Tech Serve Solutions exports worldwide with the relevant documentation, including a certificate of analysis and Safety Data Sheet, and packaging suited to the destination and transport mode.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, intended purity and destination, and our team will respond with availability, lead time and a formal quotation. Samples can be arranged for qualifying enquiries to support evaluation and method development.
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