Triethoxy-p-tolylsilane
Triethoxy-p-tolylsilane (CAS 18412-57-2), with the linear formula (C2H5O)3SiC6H4CH3 and a molecular weight of 254.40 g/mol, is an organosilicon compound. It functions as a silicon-based nucleophile. This reagent demonstrates reactivity in palladium-catalyzed cross-coupling reactions, making it a valuable tool in organic synthesis for the formation of carbon-carbon bonds.

Palladium-Catalyzed Cross-Coupling Reactions
Triethoxy-p-tolylsilane serves as a silicon-based nucleophile in various palladium-catalyzed cross-coupling methodologies. Its participation facilitates the construction of new carbon-carbon bonds, a fundamental transformation in organic chemistry.
Organosilicon Synthesis
As a trialkoxysilane derivative, this compound is integral to the field of organosilicon chemistry. It can be employed in reactions requiring the introduction of a p-tolylsilyl group or further functionalization of the silicon center.
Chemical Synthesis Reagent
This reagent is suitable for use in diverse chemical synthesis pathways where a p-tolylsilane moiety is required. Its specific reactivity profile makes it a precise tool for chemists designing complex molecular architectures.
| Molecular weight | 254.40 |
|---|---|
| Linear formula | (C2H5O)3SiC6H4CH3 |
| Assay | 97% |
| Boiling point | 104-106 °C/1.8 mmHg(lit.) |
| Density | 0.986 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.464(lit.) |
| Application | A silicon-based nucleophile shown to be reactive in Pd-catalyzed cross-coupling reactions.1 |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Triethoxy-p-tolylsilane primarily used for?
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Triethoxy-p-tolylsilane is primarily used as a silicon-based nucleophile in palladium-catalyzed cross-coupling reactions for the synthesis of complex organic molecules.
What is the CAS number and chemical formula for Triethoxy-p-tolylsilane?
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The CAS number is 18412-57-2 and the linear formula is (C2H5O)3SiC6H4CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Triethoxy-p-tolylsilane with an assay of 97%. We do not represent this product as USP, EP, or BP grade.
How should Triethoxy-p-tolylsilane be handled safely?
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Appropriate safety measures include wearing eyeshields, gloves, and a suitable respirator. Refer to the Safety Data Sheet for comprehensive handling and hazard information. It has a flash point greater than 110 °C (230 °F).
Is Triethoxy-p-tolylsilane a controlled substance?
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No, the provided data does not indicate that Triethoxy-p-tolylsilane is a controlled substance.
How can I request a sample or a quote for Triethoxy-p-tolylsilane?
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To request a sample or a quote, please use the contact form on our website or contact our sales department directly with your inquiry and preferred quantity.
How is Triethoxy-p-tolylsilane shipped and exported?
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Tech Serve Solutions is experienced in exporting chemicals worldwide and adheres to all necessary regulations for safe and compliant transportation.
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