Triethoxy[4-(trifluoromethyl)phenyl]silane

CAS 188748-63-2CF3C6H4Si(OC2H5)2Chemical Synthesis

Triethoxy[4-(trifluoromethyl)phenyl]silane (CAS: 188748-63-2; Formula: CF3C6H4Si(OC2H5)2) is an organosilicon compound with a molecular weight of 308.37 g/mol. This silicon-based nucleophile is primarily utilised in chemical synthesis, notably demonstrating reactivity in palladium-catalyzed cross-coupling reactions. Tech Serve Solutions supplies this reagent for advanced research and development purposes, adhering to strict quality controls.

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Triethoxy[4-(trifluoromethyl)phenyl]silane (CF3C6H4Si(OC2H5)2) — chemical structure, CAS 188748-63-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical SynthesisOrganometallic ReagentsOrganosiliconTrialkoxysilanes

01 /Applications

Palladium-Catalyzed Cross-Coupling Reactions

This organosilane serves as a valuable silicon-based nucleophile in palladium-catalyzed cross-coupling reactions. Its structure facilitates the introduction of the 4-(trifluoromethyl)phenyl group into various organic frameworks.

Organic Synthesis Reagent

As a functionalised trialkoxysilane, it is employed in diverse organic synthesis pathways. The trifluoromethylphenyl moiety offers unique electronic properties for creating complex molecules in research settings.

Organosilicon Chemistry

This compound is a relevant building block within the field of organosilicon chemistry. Its utility extends to the development of novel materials and intermediates leveraging the properties of silicon-carbon bonds.

02 /Properties

Molecular weight	308.37
Linear formula	CF3C6H4Si(OC2H5)2
Assay	97%
Boiling point	90-91 °C/0.2 mmHg(lit.)
Density	1.098 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.436(lit.)
Application	A silicon-based nucleophile shown to be reactive in Pd-catalyzed cross-coupling reactions.1

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305IF IN EYES

Protective equipment	Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	110 °C / 230 °F
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

188748-63-2

MDL number

MFCD05664372

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Triethoxy[4-(trifluoromethyl)phenyl]silane used for?

Triethoxy[4-(trifluoromethyl)phenyl]silane is primarily used as a silicon-based nucleophile in palladium-catalyzed cross-coupling reactions and as a reagent in general organic synthesis.

What is the CAS number and formula for Triethoxy[4-(trifluoromethyl)phenyl]silane?

The CAS number is 188748-63-2 and the chemical formula is CF3C6H4Si(OC2H5)2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Triethoxy[4-(trifluoromethyl)phenyl]silane with a minimum purity of 97%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmaceutical grade.

What are the safety and handling considerations for this chemical?

This compound is a Warning substance, indicated by GHS07 and Hazard Statement H319, meaning it causes serious eye irritation. Appropriate personal protective equipment, including eyeshields and gloves, should be worn. Always consult the Safety Data Sheet (SDS) before handling.

How is this chemical packed, shipped, and exported?

Tech Serve Solutions carefully packages and exports chemicals globally, adhering to all relevant shipping regulations. Specific packaging details are available upon request.

How can I request a quote or sample?

To request a quote or obtain a sample of Triethoxy[4-(trifluoromethyl)phenyl]silane, please contact our sales team through the website or via direct inquiry, referencing the product name and CAS number.