2-Chloroethyl ether
2-Chloroethyl ether (CAS: 111-44-4) is a chemical compound with the linear formula (ClCH2CH2)2O and a molecular weight of 143.01 g/mol. This organic ether serves as a versatile building block in chemical synthesis. It is commonly employed in organic chemistry for introducing the 2-chloroethoxy group or as a precursor in the synthesis of various organic intermediates and complex molecules. Its properties make it a valuable reagent in research and industrial applications.
- IUPAC
- 2,2′-Dichlorodiethyl ether,Bis(2-chloroethyl) ether
- Synonyms
- 2,2′-Dichlorodiethyl etherBis(2-chloroethyl) ether

Organic Synthesis Intermediate
2-Chloroethyl ether is a key intermediate in organic synthesis. It is utilised for the preparation of pharmaceuticals, agrochemicals, and other fine chemicals. Its reactive chlorine atoms allow for diverse functional group transformations.
Building Block for Heterocycles
This compound can be used as a precursor for the synthesis of cyclic ethers and other heterocyclic compounds. Its structure lends itself to cyclisation reactions, forming ring systems relevant in medicinal chemistry.
Research and Development
In academic and industrial research settings, 2-Chloroethyl ether is employed in exploring new synthetic pathways and developing novel compounds. Its defined reactivity profile supports its use in exploratory chemistry.
| Molecular weight | 143.01 |
|---|---|
| Linear formula | (ClCH2CH2)2O |
| Assay | 99% |
| Boiling point | 65-67 °C/15 mmHg(lit.) |
| Density | 1.22 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.456(lit.) |
| Vapour pressure | 0.4 mmHg (20 °C) |
| Melting point | −47 °C(lit.) |
| Storage temperature | 2-8°C |


Hazard statements
- H300Fatal if swallowed
- H310Fatal in contact with skin
- H330Fatal if inhaled
- H351Suspected of causing cancer
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P302IF ON SKIN
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 55 °C / 131 °F |
| Transport (UN / ADR) | UN 1916 6.1/PG 2 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28-40 |
| Safety statements (S) | 7/9-27-28-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloroethyl ether primarily used for?
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2-Chloroethyl ether is primarily used as a versatile building block and intermediate in organic synthesis for the preparation of pharmaceuticals, agrochemicals, and other fine chemicals, as well as in research and development for exploring new synthetic pathways.
What are the CAS number and formula for 2-Chloroethyl ether?
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The CAS number for 2-Chloroethyl ether is 111-44-4, and its linear formula is (ClCH2CH2)2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloroethyl ether with a purity of 99%. This product is typically considered a research or technical grade, and TSS does not represent it as USP, BP, or EP grade.
How should 2-Chloroethyl ether be handled safely?
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2-Chloroethyl ether is a dangerous substance and requires stringent safety precautions. It is toxic if swallowed, in contact with skin, or if inhaled (H300-H310-H330), and is suspected of causing cancer (H351). Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a suitable respirator, in a well-ventilated area. Always consult the Safety Data Sheet (SDS) before use.
How is 2-Chloroethyl ether packed, shipped, and exported?
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2-Chloroethyl ether is packed and shipped according to its hazard classification (UN 1916, Class 6.1, PG 2). Tech Serve Solutions, as a specialist global supplier, handles the export of this chemical adhering to all relevant international shipping regulations.
How can I request a sample or quote for 2-Chloroethyl ether?
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To request a sample or obtain a quote for 2-Chloroethyl ether, please contact our sales team through the website or by phone. Provide your specific requirements, and we will respond promptly.
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