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2-Chloroethanesulfonyl chloride

CAS 1622-32-8ClCH2CH2SO2ClChemical Synthesis

2-Chloroethanesulfonyl chloride (CAS: 1622-32-8), with the molecular formula ClCH2CH2SO2Cl and a molar mass of 163.02 g/mol, is a reactive chemical intermediate. It is characterised by its potent electrophilic nature, making it valuable in organic synthesis. This compound is primarily employed as a versatile reagent in the introduction of the 2-chloroethanesulfonyl group, facilitating the construction of complex organic molecules.

IUPAC
2-Chloro-1-ethanesulfonyl chloride
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2-Chloroethanesulfonyl chloride (ClCH2CH2SO2Cl) — chemical structure, CAS 1622-32-8; Chemistry, fine chemical supplied by Tech Serve Solutions
Chemical SynthesisOthersSynthetic Reagents
01 /Applications

Organic Synthesis Intermediate

2-Chloroethanesulfonyl chloride serves as a key building block in organic synthesis. It is utilized for introducing the 2-chloroethanesulfonyl moiety into various organic substrates, enabling the formation of diverse chemical structures.

Reagent for Derivatization

This compound can be employed as a derivatizing agent in analytical chemistry. Its reaction with specific functional groups allows for the modification and potential enhanced detection or separation of analytes.

Precursor in Pharmaceutical Research

In pharmaceutical research, 2-Chloroethanesulfonyl chloride may act as a precursor for synthesizing novel drug candidates or intermediates. Its reactivity allows for the elaboration of molecular scaffolds relevant to medicinal chemistry.

02 /Properties
Molecular weight163.02
Linear formulaClCH2CH2SO2Cl
Assay≥97.0% (AT)
Boiling point84-86 °C/15 mmHg(lit.)
Density1.56 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.493(lit.)n20/D 1.494
Vapour pressure15 mmHg (84 °C)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H301Toxic if swallowed
  • H314Causes severe skin burns and eye damage
  • H330Fatal if inhaled

Precautionary statements

  • P260Do not breathe dust, fume, gas, mist, vapours or spray
  • P280Wear protective gloves, clothing and eye/face protection
  • P284Wear respiratory protection
  • P301IF SWALLOWED
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point113 °C / 235.4 °F
Transport (UN / ADR)UN 3390 8(6.1) / PGI
Water hazard class (WGK, DE)3
Hazard codes (EU)T+
Risk statements (R)22-26-34
Safety statements (S)26-28-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
1622-32-8
MDL number
MFCD00007461
Beilstein registry
1751202
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Chloroethanesulfonyl chloride used for?

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2-Chloroethanesulfonyl chloride is used as an intermediate in organic synthesis, a reagent for derivatization, and a precursor in pharmaceutical research for introducing the 2-chloroethanesulfonyl group.

What are the CAS number and formula for 2-Chloroethanesulfonyl chloride?

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The CAS number is 1622-32-8, and the linear formula is ClCH2CH2SO2Cl.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-Chloroethanesulfonyl chloride with an assay of ≥97.0% (AT). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.

What are the safety and handling precautions for 2-Chloroethanesulfonyl chloride?

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2-Chloroethanesulfonyl chloride is classified as Danger (GHS05, GHS06) and carries hazard statements H301-H314-H330, indicating toxicity if swallowed and severe skin burns and eye damage, and being fatal if inhaled. Appropriate personal protective equipment, including faceshields, full-face respirators, gloves, and goggles, is essential. Handle in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive information.

How is 2-Chloroethanesulfonyl chloride packed, shipped, and exported?

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2-Chloroethanesulfonyl chloride is carefully packed according to international shipping regulations for hazardous materials. Tech Serve Solutions is experienced in exporting chemicals globally.

How can I request a sample or quote for 2-Chloroethanesulfonyl chloride?

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To request a sample or a quote for 2-Chloroethanesulfonyl chloride, please contact our sales team through the website or by phone, providing your details and requirements.

Need 2-Chloroethanesulfonyl chloride in a specific grade or volume?