2-Chloroethanesulfonyl chloride
2-Chloroethanesulfonyl chloride (CAS: 1622-32-8), with the molecular formula ClCH2CH2SO2Cl and a molar mass of 163.02 g/mol, is a reactive chemical intermediate. It is characterised by its potent electrophilic nature, making it valuable in organic synthesis. This compound is primarily employed as a versatile reagent in the introduction of the 2-chloroethanesulfonyl group, facilitating the construction of complex organic molecules.
- IUPAC
- 2-Chloro-1-ethanesulfonyl chloride

Organic Synthesis Intermediate
2-Chloroethanesulfonyl chloride serves as a key building block in organic synthesis. It is utilized for introducing the 2-chloroethanesulfonyl moiety into various organic substrates, enabling the formation of diverse chemical structures.
Reagent for Derivatization
This compound can be employed as a derivatizing agent in analytical chemistry. Its reaction with specific functional groups allows for the modification and potential enhanced detection or separation of analytes.
Precursor in Pharmaceutical Research
In pharmaceutical research, 2-Chloroethanesulfonyl chloride may act as a precursor for synthesizing novel drug candidates or intermediates. Its reactivity allows for the elaboration of molecular scaffolds relevant to medicinal chemistry.
| Molecular weight | 163.02 |
|---|---|
| Linear formula | ClCH2CH2SO2Cl |
| Assay | ≥97.0% (AT) |
| Boiling point | 84-86 °C/15 mmHg(lit.) |
| Density | 1.56 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.493(lit.)n20/D 1.494 |
| Vapour pressure | 15 mmHg (84 °C) |


Hazard statements
- H301Toxic if swallowed
- H314Causes severe skin burns and eye damage
- H330Fatal if inhaled
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3390 8(6.1) / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 22-26-34 |
| Safety statements (S) | 26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloroethanesulfonyl chloride used for?
+
2-Chloroethanesulfonyl chloride is used as an intermediate in organic synthesis, a reagent for derivatization, and a precursor in pharmaceutical research for introducing the 2-chloroethanesulfonyl group.
What are the CAS number and formula for 2-Chloroethanesulfonyl chloride?
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The CAS number is 1622-32-8, and the linear formula is ClCH2CH2SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloroethanesulfonyl chloride with an assay of ≥97.0% (AT). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for 2-Chloroethanesulfonyl chloride?
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2-Chloroethanesulfonyl chloride is classified as Danger (GHS05, GHS06) and carries hazard statements H301-H314-H330, indicating toxicity if swallowed and severe skin burns and eye damage, and being fatal if inhaled. Appropriate personal protective equipment, including faceshields, full-face respirators, gloves, and goggles, is essential. Handle in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive information.
How is 2-Chloroethanesulfonyl chloride packed, shipped, and exported?
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2-Chloroethanesulfonyl chloride is carefully packed according to international shipping regulations for hazardous materials. Tech Serve Solutions is experienced in exporting chemicals globally.
How can I request a sample or quote for 2-Chloroethanesulfonyl chloride?
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To request a sample or a quote for 2-Chloroethanesulfonyl chloride, please contact our sales team through the website or by phone, providing your details and requirements.
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