4-(Difluoromethoxy)benzoic acid
4-(Difluoromethoxy)benzoic acid (CAS: 4837-20-1) is a fluorinated organic building block with the linear formula F₂CHO C₆H₄ CO₂H and a molecular weight of 188.13 g/mol. This compound functions as a key intermediate in organic synthesis. Its difluoromethyl ether group and carboxylic acid functionality make it valuable for introducing specific structural motifs in the development of new materials and active pharmaceutical ingredients. Available at 98% purity, it serves as a reliable reagent for research and development.
Pharmaceutical Intermediate
Utilised in the synthesis of novel drug candidates where the difluoromethoxyaryl moiety is desired for modulating pharmacokinetic properties or biological activity.
Agrochemical Synthesis
Serves as a building block for the development of new pesticides and herbicides, leveraging the unique electronic and lipophilic characteristics imparted by the difluoromethoxy group.
Materials Science
Incorporated into the design of advanced materials, such as liquid crystals or functional polymers, due to its specific structural and electronic properties.
Organic Synthesis Reagent
A versatile reagent for organic chemists requiring the introduction of the 4-(difluoromethoxy)benzoyl group into complex molecular architectures.
| Molecular weight | 188.13 |
|---|---|
| Linear formula | F2CHOC6H4CO2H |
| Assay | 98% |
| Melting point | 169-171 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Difluoromethoxy)benzoic acid used for?
+
4-(Difluoromethoxy)benzoic acid is primarily used as a building block and intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials.
What are the CAS number and formula for 4-(Difluoromethoxy)benzoic acid?
+
The CAS number is 4837-20-1, and its linear formula is F₂CHO C₆H₄ CO₂H.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 4-(Difluoromethoxy)benzoic acid at a purity of 98%. We do not represent this product as USP, BP, or EP grade.
How should 4-(Difluoromethoxy)benzoic acid be handled?
+
Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation. Avoid breathing dust. Causes skin irritation, serious eye irritation, and may cause respiratory irritation.
Is 4-(Difluoromethoxy)benzoic acid a controlled substance?
+
The provided data does not indicate that 4-(Difluoromethoxy)benzoic acid is a controlled substance.
How is this product packaged and shipped globally?
+
Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, providing various packaging options suitable for international shipment.
How can I request a quote or sample?
+
To request a quote or sample of 4-(Difluoromethoxy)benzoic acid, please contact our sales team through the website or designated inquiry channels.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis