4-(Difluoromethoxy)nitrobenzene
4-(Difluoromethoxy)nitrobenzene (CAS 1544-86-1) is an organic compound with the linear formula F₂CHOC₆H₄NO₂ and a molecular weight of 189.12 g/mol. This nitro compound serves as a valuable building block in organic synthesis and chemical research. It is supplied by Tech Serve Solutions with an assay of 97%, suitable for various laboratory and industrial applications requiring precise chemical intermediates.

Organic Synthesis Intermediate
4-(Difluoromethoxy)nitrobenzene is utilised as a key intermediate in the synthesis of more complex organic molecules. Its unique difluoromethoxy and nitro functionalities allow for diverse chemical transformations.
Pharmaceutical Research
This compound can be employed in the development of novel pharmaceutical agents. The presence of fluorine atoms can influence the pharmacokinetic properties of drug candidates.
Agrochemical Development
It may find application in the synthesis of new agrochemicals, contributing to the development of crop protection agents. The nitro group is a common feature in some pesticide structures.
Materials Science
The molecule's structure lends itself to exploration in materials science, potentially for the creation of specialised polymers or functional materials.
| Molecular weight | 189.12 |
|---|---|
| Linear formula | F2CHOC6H4NO2 |
| Assay | 97% |
| Melting point | 37-40 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Difluoromethoxy)nitrobenzene used for?
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4-(Difluoromethoxy)nitrobenzene is primarily used as a building block in organic synthesis, including applications in pharmaceutical research and agrochemical development.
What is the CAS number and chemical formula for 4-(Difluoromethoxy)nitrobenzene?
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The CAS number is 1544-86-1 and the linear chemical formula is F₂CHOC₆H₄NO₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Difluoromethoxy)nitrobenzene with an assay of 97%. This is a technical grade product and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 4-(Difluoromethoxy)nitrobenzene be handled safely?
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Handling requires appropriate personal protective equipment including a dust mask (N95 recommended), eyeshields, face shields, and gloves. It is classified as harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation (H302, H315, H319, H335).
Is 4-(Difluoromethoxy)nitrobenzene available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-(Difluoromethoxy)nitrobenzene, adhering to all necessary regulations for international shipment.
How can I request a quote or sample?
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To request a quote or a sample of 4-(Difluoromethoxy)nitrobenzene, please contact our sales team through the website or provide your requirements via email.
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