4-(Difluoromethoxy)iodobenzene
4-(Difluoromethoxy)iodobenzene (CAS: 128140-82-9) is an organic compound with the molecular formula F₂CHOC₆H₄I and a molecular weight of 270.02 g/mol. This iodinated aromatic ether serves as a valuable building block in organic synthesis, particularly in the pharmaceutical and agrochemical industries. Its structure facilitates various cross-coupling reactions and other transformations, enabling the construction of complex molecular architectures.
Pharmaceutical Intermediate Synthesis
4-(Difluoromethoxy)iodobenzene is utilised as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). The difluoromethoxy group can impart desirable pharmacokinetic properties, while the iodine atom provides a reactive handle for further functionalisation.
Agrochemical Development
This compound finds application in the development of novel agrochemicals. Its incorporation into candidate molecules can influence biological activity and environmental persistence, contributing to the creation of advanced crop protection agents.
Materials Science Research
As a functionalised aromatic compound, it can be explored in materials science for the synthesis of speciality polymers or organic electronic materials, where the difluoromethoxy and iodo substituents offer unique electronic and structural characteristics.
Fine Chemical Synthesis
It serves as a versatile building block in general organic synthesis, allowing chemists to introduce the 4-(difluoromethoxy)phenyl moiety into a wide range of target molecules for research and development purposes.
| Molecular weight | 270.02 |
|---|---|
| Linear formula | F2CHOC6H4I |
| Assay | 97% |
| Boiling point | 217-219 °C(lit.) |
| Density | 1.871 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.548(lit.) |
Hazard statements
- H315Causes skin irritation
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 38 |
| Safety statements (S) | 37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Difluoromethoxy)iodobenzene used for?
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4-(Difluoromethoxy)iodobenzene is primarily used as a building block in organic synthesis, particularly for creating intermediates in the pharmaceutical and agrochemical industries. It is also valuable in materials science research.
What is the CAS number and molecular formula for 4-(Difluoromethoxy)iodobenzene?
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The CAS number is 128140-82-9, and the linear molecular formula is F₂CHOC₆H₄I.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Difluoromethoxy)iodobenzene with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should 4-(Difluoromethoxy)iodobenzene be handled?
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This compound is classified as a warning substance and can cause skin irritation (H315). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, should be worn during handling to avoid contact and inhalation.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions offers expert packing, shipping, and global export of chemicals. Please contact us for specific details regarding packaging options and international logistics for 4-(Difluoromethoxy)iodobenzene.
How can I request a sample or quote for 4-(Difluoromethoxy)iodobenzene?
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To request a sample or a quotation for 4-(Difluoromethoxy)iodobenzene, please use the 'Request a Quote' or 'Request a Sample' form on our website, or contact our sales team directly.
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