4-(Difluoromethoxy)aniline
Tech Serve Solutions offers 4-(Difluoromethoxy)aniline (CAS: 22236-10-8), a fluorinated organic building block with the linear formula F₂CHOC₆H₄NH₂ and a molecular weight of 159.13 g/mol. This aniline derivative is characterised by its difluoromethyl ether substituent. It serves as a valuable intermediate in the synthesis of complex organic molecules, particularly within the pharmaceutical and agrochemical industries.
Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs). The difluoromethoxy group can enhance metabolic stability and lipophilicity of drug candidates.
Agrochemical Synthesis
Serves as a building block for the development of novel pesticides and herbicides. Fluorinated compounds often exhibit unique biological activity.
Organic Synthesis
A versatile reagent for introducing the 4-(difluoromethoxy)phenyl moiety into various organic structures through standard amination reactions or further functionalization.
Material Science
Potential application in the synthesis of functional materials where fluorinated aromatic amines can impart specific electronic or physical properties.
| Molecular weight | 159.13 |
|---|---|
| Linear formula | F2CHOC6H4NH2 |
| Assay | 98% |
| Boiling point | 231 °C(lit.) |
| Density | 1.283 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.505(lit.) |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Difluoromethoxy)aniline used for?
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4-(Difluoromethoxy)aniline (CAS: 22236-10-8) is primarily used as an intermediate in organic synthesis, particularly for pharmaceuticals and agrochemicals, owing to its difluoromethoxy functional group.
What is the CAS number and formula for 4-(Difluoromethoxy)aniline?
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The CAS number is 22236-10-8, and the linear formula is F₂CHOC₆H₄NH₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Difluoromethoxy)aniline with an assay of 98%. This product is typically considered a research or technical grade; we do not represent it as USP, BP, or EP grade.
How should 4-(Difluoromethoxy)aniline be handled safely?
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4-(Difluoromethoxy)aniline is classified as Danger. It is toxic if swallowed and causes skin and serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including gloves, eyeshields, and a suitable respirator, in a well-ventilated area.
Is 4-(Difluoromethoxy)aniline a controlled substance?
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The provided data does not indicate that 4-(Difluoromethoxy)aniline is a controlled substance.
How is 4-(Difluoromethoxy)aniline exported and shipped?
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As a global supplier, Tech Serve Solutions professionally packages and exports chemicals like 4-(Difluoromethoxy)aniline in compliance with international shipping regulations for hazardous materials (UN 2811, Class 6.1, PGIII).
How can I request a sample or quote for 4-(Difluoromethoxy)aniline?
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To request a sample or a quote for 4-(Difluoromethoxy)aniline, please contact our sales team through the website or by phone, providing your required quantity and shipping details.
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