4-(Difluoromethoxy)benzaldehyde
4-(Difluoromethoxy)benzaldehyde (CAS 73960-07-3) is a fluorinated organic compound with the linear formula F<sub>2</sub>CHOC<sub>6</sub>H<sub>4</sub>CHO and a molecular weight of 172.13 g/mol. As an aldehyde and a difluoromethyl-containing building block, it is employed in chemical synthesis. Its structure makes it a valuable intermediate for introducing the difluoromethoxy group into more complex molecules, particularly in the fields of medicinal chemistry and materials science.

Organic Synthesis Intermediate
This compound serves as a key building block in the synthesis of complex organic molecules. The presence of both an aldehyde group and a difluoromethoxy moiety allows for diverse chemical transformations.
Medicinal Chemistry
The difluoromethoxy group is often incorporated into pharmaceutical candidates to modulate properties such as lipophilicity, metabolic stability, and binding affinity. 4-(Difluoromethoxy)benzaldehyde is a useful starting material for such research.
Materials Science
Fluorinated organic compounds are utilized in the development of advanced materials. This aldehyde can be a precursor for synthesizing specialty polymers, liquid crystals, or other functional materials where fluorine incorporation is desired.
| Molecular weight | 172.13 |
|---|---|
| Linear formula | F2CHOC6H4CHO |
| Assay | 95% |
| Boiling point | 222 °C(lit.) |
| Density | 1.302 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.503(lit.) |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Flash point | 109 °C / 228.2 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Difluoromethoxy)benzaldehyde used for?
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4-(Difluoromethoxy)benzaldehyde is primarily used as an intermediate and building block in organic synthesis, particularly in medicinal chemistry and materials science for introducing the difluoromethoxy group into target molecules.
What are the CAS number and linear formula for 4-(Difluoromethoxy)benzaldehyde?
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The CAS number for 4-(Difluoromethoxy)benzaldehyde is 73960-07-3, and its linear formula is F<sub>2</sub>CHOC<sub>6</sub>H<sub>4</sub>CHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Difluoromethoxy)benzaldehyde with a minimum assay of 95%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the main safety hazards associated with this chemical?
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4-(Difluoromethoxy)benzaldehyde is combustible and has a high flash point (109 °C / 228.2 °F). It is classified under WGK 2. We recommend using Eyeshields and Gloves for personal protection. Please consult the Safety Data Sheet for comprehensive handling information.
How is 4-(Difluoromethoxy)benzaldehyde typically packed and exported?
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This chemical is typically packed in appropriate containers to ensure safe transit and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a quote or sample for 4-(Difluoromethoxy)benzaldehyde?
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To request a quote or a sample, please contact our sales department via the website or by phone, providing your contact details and the product CAS number (73960-07-3).
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