4-(Difluoromethyl)pyridine
4-(Difluoromethyl)pyridine (CAS: 82878-62-4), with the molecular formula C6H5F2N and a molecular weight of 129.11 g/mol, is a specialised fluorinated heterocyclic building block. It is valuable in organic synthesis for introducing the difluoromethylpyridine moiety. This compound serves as a key intermediate in the development of novel molecules, particularly within the pharmaceutical and agrochemical sectors, owing to the unique properties imparted by the difluoromethyl group.
Pharmaceutical Intermediate
This fluorinated pyridine derivative is employed in the synthesis of complex pharmaceutical compounds. The difluoromethyl group can modulate pharmacokinetic properties such as metabolic stability and lipophilicity.
Agrochemical Development
It acts as a crucial building block for novel agrochemicals, including herbicides, insecticides, and fungicides. Incorporation of the difluoromethylpyridine structure can enhance bioactivity and environmental persistence profiles.
Materials Science
The unique electronic and structural properties of 4-(Difluoromethyl)pyridine make it a candidate for research in advanced materials. It can be explored for applications in functional polymers or organic electronics.
Organic Synthesis Reagent
As a versatile building block, it is utilised in various cross-coupling reactions and functional group transformations within academic and industrial research laboratories.
| Molecular weight | 129.11 |
|---|---|
| Empirical formula | C6H5F2N |
| Assay | 97% |
| Density | 1.207 g/mL at 25 °C |
| Refractive index | n20/D 1.463 |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | 51 °C / 123.8 °F |
|---|---|
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Difluoromethyl)pyridine used for?
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4-(Difluoromethyl)pyridine is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals, owing to its difluoromethylpyridine moiety.
What are the CAS number and formula for 4-(Difluoromethyl)pyridine?
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The CAS number for 4-(Difluoromethyl)pyridine is 82878-62-4, and its molecular formula is C6H5F2N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Difluoromethyl)pyridine with a minimum assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 4-(Difluoromethyl)pyridine be handled safely?
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4-(Difluoromethyl)pyridine is a flammable liquid and vapour (H226), causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle in a well-ventilated area, away from ignition sources, wearing appropriate personal protective equipment.
How is 4-(Difluoromethyl)pyridine packaged and shipped?
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4-(Difluoromethyl)pyridine is packaged according to safety regulations for flammable liquids and exported globally by Tech Serve Solutions.
How can I request a sample or quote for 4-(Difluoromethyl)pyridine?
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To request a sample or obtain a quotation for 4-(Difluoromethyl)pyridine, please contact our sales department through the website or by phone.
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