5-Chloro-2-hydroxy-3-nitropyridine
5-Chloro-2-hydroxy-3-nitropyridine (CAS: 21427-61-2), with the molecular formula C5H3ClN2O3, is a halogenated heterocyclic compound. It serves as a valuable building block in chemical synthesis, particularly within the pyridine and heterocyclic chemistry fields. This compound is typically supplied at an assay of 97% and is utilised in research and development settings for the creation of more complex molecules. Its structure lends itself to various synthetic transformations.
- IUPAC
- 5-Chloro-3-nitro-2-pyridinol

Organic Synthesis Intermediate
5-Chloro-2-hydroxy-3-nitropyridine functions as a key intermediate in the synthesis of diverse organic compounds. Its reactive sites allow for further functionalisation, making it useful in multi-step synthetic pathways.
Heterocyclic Chemistry Research
This pyridine derivative is employed in academic and industrial research for exploring novel heterocyclic structures. It aids in the development of new chemical entities with potential applications in pharmaceuticals and materials science.
Building Block for Specialty Chemicals
As a versatile building block, it contributes to the construction of complex molecules requiring a substituted pyridine core. This includes its use in creating new agrochemicals or functional materials.
| Molecular weight | 174.54 |
|---|---|
| Empirical formula | C5H3ClN2O3 |
| Assay | 97% |
| Melting point | 232-236 °C |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-2-hydroxy-3-nitropyridine used for?
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5-Chloro-2-hydroxy-3-nitropyridine is primarily used as a building block and intermediate in organic synthesis, particularly for creating novel heterocyclic compounds and specialty chemicals in research and development settings.
What is the CAS number and formula for 5-Chloro-2-hydroxy-3-nitropyridine?
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The CAS number for 5-Chloro-2-hydroxy-3-nitropyridine is 21427-61-2, and its molecular formula is C5H3ClN2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Chloro-2-hydroxy-3-nitropyridine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for 5-Chloro-2-hydroxy-3-nitropyridine?
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This compound is classified as Danger. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, faceshields, and gloves, must be used. Handle in a well-ventilated area.
How is 5-Chloro-2-hydroxy-3-nitropyridine packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, ensuring appropriate packaging for safe transit. Please contact us for specific shipping and export details.
How can I request a sample or quote for 5-Chloro-2-hydroxy-3-nitropyridine?
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To request a sample or a quotation for 5-Chloro-2-hydroxy-3-nitropyridine, please use the contact form on our website or reach out to our sales team directly.
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