5-Chloro-2-hydroxypyridine
5-Chloro-2-hydroxypyridine (CAS: 4214-79-3) is a pyridine derivative with the molecular formula C5H4ClNO and a molecular weight of 129.54 g/mol. This compound serves as a valuable intermediate in organic synthesis. It has been utilised in biochemical research, particularly in studies concerning the effects of compounds like dicumarol and mitomycin C on enzymatic processes such as xanthine dehydrogenase activity. Available at 97% purity, it is supplied by Tech Serve Solutions for research and synthesis purposes.
- IUPAC
- 5-Chloro-2-pyridinol

Biochemical Research Studies
Utilised in research to investigate enzymatic mechanisms, including the effect of dicumarol on xanthine dehydrogenase activity. It has also been employed in studies examining the bioreduction of mitomycin C by xanthine dehydrogenase.
Organic Synthesis Intermediate
Serves as a key building block in the synthesis of more complex organic molecules. Its heterocyclic structure with halogen and hydroxyl substituents offers versatile reactivity for chemical transformations.
Halogenated Heterocycle Chemistry
As a halogenated pyridine derivative, it is relevant in the field of heterocyclic chemistry, contributing to the development of novel compounds with potential applications in various chemical sectors.
| Molecular weight | 129.54 |
|---|---|
| Empirical formula | C5H4ClNO |
| Assay | 97% |
| Application | 5-chloro-2-hydroxypyridine (5-Chloro-2-pyridinol) was used to study the effect of dicumarol on xanthine dehydrogenase1 and mechanism of mitomycin C bioreduction by xanthine dehydrogenase2. |
| Melting point | 163-165 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-2-hydroxypyridine used for?
+
5-Chloro-2-hydroxypyridine (CAS: 4214-79-3) is primarily used as an intermediate in organic synthesis and in biochemical research to study enzymatic mechanisms.
What are the CAS number and chemical formula for 5-Chloro-2-hydroxypyridine?
+
The CAS number is 4214-79-3, and the chemical formula is C5H4ClNO.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 5-Chloro-2-hydroxypyridine with an assay of 97%.
What are the safety considerations when handling 5-Chloro-2-hydroxypyridine?
+
5-Chloro-2-hydroxypyridine is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is 5-Chloro-2-hydroxypyridine packed and shipped?
+
Tech Serve Solutions exports fine chemicals globally. Specific packaging details are available upon request, and shipments comply with international regulations for chemical transport.
How can I request a sample or quote for 5-Chloro-2-hydroxypyridine?
+
To request a sample or a quotation, please contact our sales department through the website or by phone, referencing the product name and CAS number 4214-79-3.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis