2-Fluoro-5-(trifluoromethyl)phenol
2-Fluoro-5-(trifluoromethyl)phenol (CAS: 141483-15-0), with the molecular formula FC6H3(CF3)OH and a molecular weight of 180.10 g/mol, is a fluorinated organic building block. This compound is characterised by its phenolic hydroxyl group and a trifluoromethyl substituent on the aromatic ring, making it a valuable intermediate in complex organic synthesis. It is frequently utilised in the development of pharmaceuticals and advanced materials.
Pharmaceutical Intermediate
This fluorinated phenol serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs). Its specific functional groups allow for diverse chemical transformations required in drug discovery and development.
Agrochemical Synthesis
The presence of fluorine and a trifluoromethyl group makes it suitable for incorporation into novel agrochemical compounds, potentially enhancing their efficacy and stability.
Materials Science
Used in the development of specialty polymers and advanced materials where fluorination can impart unique properties such as thermal stability and chemical resistance.
Organic Synthesis Reagent
A versatile reagent for introducing fluorinated phenolic moieties into organic molecules during multi-step synthetic procedures.
| Molecular weight | 180.10 |
|---|---|
| Linear formula | FC6H3(CF3)OH |
| Assay | 97% |
| Boiling point | 146 °C(lit.) |
| Density | 1.436 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.439(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 57 °C / 134.6 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-5-(trifluoromethyl)phenol used for?
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2-Fluoro-5-(trifluoromethyl)phenol is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and advanced materials due to its fluorinated structure.
What are the CAS number and chemical formula for 2-Fluoro-5-(trifluoromethyl)phenol?
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The CAS number for 2-Fluoro-5-(trifluoromethyl)phenol is 141483-15-0, and its chemical formula is FC6H3(CF3)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-5-(trifluoromethyl)phenol with a minimum assay of 97%. This product is supplied for research and development purposes and is not intended for USP, BP, EP, or other pharmacopoeia applications unless explicitly stated.
How should 2-Fluoro-5-(trifluoromethyl)phenol be handled safely?
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2-Fluoro-5-(trifluoromethyl)phenol is a flammable liquid and vapour (H226) and is harmful if swallowed, in contact with skin, or if inhaled (H302, H312, H332). It also causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including safety glasses, face shields, gloves, and suitable respiratory protection, must be used. Handle in a well-ventilated area.
How is 2-Fluoro-5-(trifluoromethyl)phenol packed and exported?
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Tech Serve Solutions offers 2-Fluoro-5-(trifluoromethyl)phenol in various pack sizes suitable for laboratory and industrial use. We are experienced in exporting chemicals globally, adhering to all relevant shipping and customs regulations for hazardous materials (UN 1993).
How can I request a quote or sample for 2-Fluoro-5-(trifluoromethyl)phenol?
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To request a quote or a sample of 2-Fluoro-5-(trifluoromethyl)phenol, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.
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