2-Fluoro-5-(trifluoromethyl)phenyl isothiocyanate

CAS 302912-40-9FC6H3(CF3)NCSChemical Synthesis

2-Fluoro-5-(trifluoromethyl)phenyl isothiocyanate (CAS: 302912-40-9; Formula: FC6H3(CF3)NCS; MW: 221.17) is a fluorinated organic compound supplied by Tech Serve Solutions. This chemical functions as a versatile building block in organic synthesis. Its unique structure, incorporating both fluorine and trifluoromethyl groups alongside the isothiocyanate moiety, makes it valuable for creating complex molecular architectures in research and development settings. Available at 97% purity.

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2-Fluoro-5-(trifluoromethyl)phenyl isothiocyanate (FC6H3(CF3)NCS) — chemical structure, CAS 302912-40-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksChemical SynthesisOrganic Building BlocksSulfur CompoundsThiocyanates/Isothiocyanates

01 /Applications

Organic Synthesis Intermediate

This isothiocyanate serves as a key intermediate in the synthesis of novel organic compounds. Its reactive isothiocyanate group readily participates in addition reactions with nucleophiles, facilitating the construction of heterocyclic systems and other complex organic molecules.

Research and Development

Utilised in R&D for exploring new chemical entities and reaction pathways. The presence of fluorine atoms can impart unique electronic and lipophilic properties to target molecules, which is often desirable in medicinal chemistry and materials science.

Building Block for Specialty Chemicals

Serves as a foundational component for the creation of specialty chemicals, including potential pharmaceutical intermediates and agrochemicals. The trifluoromethyl group offers metabolic stability and lipophilicity.

02 /Properties

Molecular weight	221.17
Linear formula	FC6H3(CF3)NCS
Assay	97%
Boiling point	202-209 °C(lit.)
Density	1.42 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.54(lit.)

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	98 °C / 208.4 °F
Transport (UN / ADR)	UN 1760 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34
Safety statements (S)	26-27-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

302912-40-9

MDL number

MFCD02683532

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Fluoro-5-(trifluoromethyl)phenyl isothiocyanate used for?

This compound is primarily used as a building block and intermediate in organic synthesis and research and development for creating novel organic compounds, including potential pharmaceutical and agrochemical agents.

What is the CAS number and molecular formula for this chemical?

The CAS number is 302912-40-9 and the molecular formula is FC6H3(CF3)NCS.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product at a purity of 97%. We do not represent this product as meeting USP, BP, EP, or other pharmacopoeia standards.

How should 2-Fluoro-5-(trifluoromethyl)phenyl isothiocyanate be handled safely?

This compound is classified as Danger, with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment including full-face shields, gloves, goggles, and suitable respirators (e.g., type ABEK) must be used. Handle in a well-ventilated area, following strict safety protocols to avoid contact and inhalation.

How is this chemical packed and exported?

This chemical is shipped as UN 1760, hazard class 8, Packing Group II, indicating it is a corrosive material requiring specialised packaging and handling for domestic and international export.

How can I request a quote or sample?

To request a quote or a sample, please contact our sales team through the website or via direct inquiry, providing your specific requirements and shipping details.