2-Fluoro-5-(trifluoromethyl)benzoyl chloride
2-Fluoro-5-(trifluoromethyl)benzoyl chloride (CAS: 207981-46-2) is a fluorinated organic compound with the linear formula FC₆H₃(CF₃)COCl and a molecular weight of 226.56 g/mol. This acid halide serves as a valuable building block in organic synthesis, particularly for introducing the 2-fluoro-5-(trifluoromethyl)benzoyl moiety into various molecules. Its reactivity makes it suitable for derivatisation in the development of novel chemical entities.
Organic Synthesis Intermediate
This compound is primarily utilised as an intermediate in complex organic synthesis pathways. It allows for the facile introduction of a fluorinated benzoyl group, valuable in the development of pharmaceuticals and agrochemicals.
Fluorinated Building Block
As a fluorinated building block, it is instrumental in the synthesis of advanced materials and specialised chemical products requiring the unique properties imparted by fluorine atoms.
Reagent in Derivatisation
Its acyl chloride functionality makes it a reactive reagent for derivatising alcohols, amines, and other nucleophiles, enabling the formation of esters, amides, and related compounds.
| Molecular weight | 226.56 |
|---|---|
| Linear formula | FC6H3(CF3)COCl |
| Assay | 97% |
| Boiling point | 191 °C(lit.) |
| Density | 1.499 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.468(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 93 °C / 199.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-5-(trifluoromethyl)benzoyl chloride used for?
+
2-Fluoro-5-(trifluoromethyl)benzoyl chloride is used as an intermediate and building block in organic synthesis, particularly for introducing the 2-fluoro-5-(trifluoromethyl)benzoyl group into various molecular structures.
What are the CAS number and formula for 2-Fluoro-5-(trifluoromethyl)benzoyl chloride?
+
The CAS number is 207981-46-2 and the linear formula is FC₆H₃(CF₃)COCl.
What grade and purity does Tech Serve Solutions supply for 2-Fluoro-5-(trifluoromethyl)benzoyl chloride?
+
Tech Serve Solutions supplies 2-Fluoro-5-(trifluoromethyl)benzoyl chloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2-Fluoro-5-(trifluoromethyl)benzoyl chloride be handled safely?
+
This compound is classified as Danger with hazard statement H314 (causes severe skin burns and eye damage). Appropriate personal protective equipment including full-face respirators, gloves, and eye protection is required. Handle only in well-ventilated areas. Refer to the safety data sheet for comprehensive handling procedures.
Is 2-Fluoro-5-(trifluoromethyl)benzoyl chloride packed, shipped, or exported by TSS?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Fluoro-5-(trifluoromethyl)benzoyl chloride.
How can I request a sample or quote for 2-Fluoro-5-(trifluoromethyl)benzoyl chloride?
+
Please contact our sales team directly through our website or by phone to request a sample or a quotation for 2-Fluoro-5-(trifluoromethyl)benzoyl chloride.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis