2-Fluoro-5-(trifluoromethyl)benzaldehyde
2-Fluoro-5-(trifluoromethyl)benzaldehyde (CAS: 146137-78-2, Formula: F3CC6H3(F)CHO) is a specialised aromatic aldehyde with a molecular weight of 192.11 g/mol. Possessing both a fluorine and a trifluoromethyl group on the benzene ring, this compound serves as a valuable building block in organic synthesis. It is frequently employed in the development of advanced materials and complex organic molecules within the chemical and pharmaceutical industries.
Pharmaceutical Intermediate
Utilised as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its unique fluorinated structure can impart desirable pharmacokinetic properties to drug candidates.
Agrochemical Synthesis
Serves as a building block for the creation of novel agrochemicals, including herbicides and pesticides. The trifluoromethyl and fluorine substituents can enhance biological activity and stability.
Materials Science
Applied in the development of advanced materials, such as liquid crystals and polymers. The incorporation of fluorinated aromatic rings can modify material properties like thermal stability and dielectric constant.
Organic Synthesis Reagent
A versatile reagent in general organic synthesis for introducing a fluorinated benzaldehyde moiety. It participates in various reactions like Wittig, Grignard, and condensation reactions.
| Molecular weight | 192.11 |
|---|---|
| Linear formula | F3CC6H3(F)CHO |
| Assay | 97% |
| Boiling point | 176 °C(lit.) |
| Density | 1.36 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.452(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-5-(trifluoromethyl)benzaldehyde used for?
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2-Fluoro-5-(trifluoromethyl)benzaldehyde is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. It also functions as a versatile reagent in general organic synthesis.
What are the CAS number and formula for this chemical?
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The CAS number for 2-Fluoro-5-(trifluoromethyl)benzaldehyde is 146137-78-2, and its molecular formula is F3CC6H3(F)CHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-5-(trifluoromethyl)benzaldehyde with an assay of 97%. This product is typically considered a technical or research grade and is not represented as USP, BP, EP, or any other pharmacopoeia standard.
What are the safety and handling precautions for 2-Fluoro-5-(trifluoromethyl)benzaldehyde?
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This compound is classified as a Warning (GHS07) and is associated with hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). It is recommended to use a dust mask type N95, eyeshields, and gloves when handling. Ensure adequate ventilation.
How is 2-Fluoro-5-(trifluoromethyl)benzaldehyde packed and exported?
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Tech Serve Solutions packs and exports chemicals with strict adherence to international shipping regulations. Packaging details are confirmed upon order, and export documentation is handled by our experienced logistics team.
How can I request a sample or a quote for 2-Fluoro-5-(trifluoromethyl)benzaldehyde?
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To request a sample or a quote, please use the 'Request a Quote' form on our website or contact our sales department directly with your inquiry.
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