2-Fluoro-4-nitrotoluene
2-Fluoro-4-nitrotoluene (CAS: 1427-07-2), with the chemical formula CH3C6H3(NO2)F and a molecular weight of 155.13 g/mol, is a valuable organic intermediate. It functions as a key building block in organic synthesis, particularly in the development of fluorinated compounds. This nitroaromatic compound is recognised for its utility in the precise construction of more complex molecules within the chemical and pharmaceutical industries.
Synthesis of Carboxylic Acids
2-Fluoro-4-nitrotoluene has been employed as a precursor in the synthesis of 2-fluoro-4-nitrobenzoic acid. This transformation highlights its role in introducing specific functional groups for further chemical modification.
Fluorinated Organic Building Block
As a fluorinated aromatic compound, it serves as a versatile building block for introducing fluorine atoms into organic molecules. This is crucial in medicinal chemistry and materials science, where fluorination can significantly alter a compound's properties.
Intermediate in Chemical Synthesis
Its structure, featuring both a nitro group and a fluorine atom on a toluene backbone, makes it a useful intermediate for various organic transformations. These can include reduction of the nitro group or nucleophilic aromatic substitution reactions.
| Molecular weight | 155.13 |
|---|---|
| Linear formula | CH3C6H3(NO2)F |
| Assay | 98% |
| Boiling point | 65-68 °C/2 mmHg(lit.) |
| Application | 2-Fluoro-4-nitrotoluene was used in the synthesis of 2-fluoro-4-nitrobenzoic acid1. |
| Melting point | 31-35 °C(lit.) |
Hazard statements
- H228Flammable solid
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 73 °C / 163.4 °F |
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-4-nitrotoluene used for?
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2-Fluoro-4-nitrotoluene is primarily used as a building block in organic synthesis, particularly for creating fluorinated organic compounds and intermediates like 2-fluoro-4-nitrobenzoic acid.
What is the CAS number and chemical formula for 2-Fluoro-4-nitrotoluene?
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The CAS number is 1427-07-2 and the chemical formula is CH3C6H3(NO2)F.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-4-nitrotoluene with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for 2-Fluoro-4-nitrotoluene?
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2-Fluoro-4-nitrotoluene is classified as a Danger substance. It is flammable (Flash Point 73 °C) and harmful if swallowed, inhaled, or in contact with skin. It can cause skin and serious eye irritation, and respiratory irritation. Appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves must be worn. Store away from heat and open flames. In case of contact, rinse immediately and thoroughly with water.
Is 2-Fluoro-4-nitrotoluene a controlled substance?
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The provided data does not indicate that 2-Fluoro-4-nitrotoluene is a controlled substance.
How is 2-Fluoro-4-nitrotoluene packed, shipped, and exported?
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2-Fluoro-4-nitrotoluene is packed and shipped according to UN 1325, Class 4.1, Packing Group II regulations, suitable for international export.
How can I request a sample or a quote for 2-Fluoro-4-nitrotoluene?
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To request a sample or a quote for 2-Fluoro-4-nitrotoluene, please contact the Tech Serve Solutions sales department via our website or listed contact details.
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