2-Fluoro-4-nitroanisole
2-Fluoro-4-nitroanisole (CAS: 455-93-6; Formula: FC6H3(NO2)OCH3; MW: 171.13) is a fluorinated aromatic compound supplied by Tech Serve Solutions. It serves as a valuable intermediate and building block in organic synthesis, particularly for introducing the 2-fluoro-4-methoxyphenyl moiety into larger molecules. Its primary applications lie in the research and development of pharmaceuticals, agrochemicals, and specialty materials where precise structural modification is required.

Pharmaceutical Intermediates
2-Fluoro-4-nitroanisole is utilised in the synthesis of active pharmaceutical ingredients (APIs). The fluoro and nitro groups provide reactive sites for further chemical transformations, enabling the construction of complex drug molecules.
Agrochemical Development
This compound can serve as a key building block in the development of novel pesticides, herbicides, and fungicides. Its specific structural features can contribute to the biological activity of the final agrochemical product.
Materials Science Research
The unique electronic and structural properties imparted by the fluorine and nitro substituents make 2-Fluoro-4-nitroanisole a useful component in the synthesis of advanced materials and functional organic molecules.
Organic Synthesis Reagent
As a versatile building block, it is employed in various organic reactions to introduce specific functional groups and aromatic structures in research laboratories and pilot-scale synthesis.
| Molecular weight | 171.13 |
|---|---|
| Linear formula | FC6H3(NO2)OCH3 |
| Assay | 98% |
| Melting point | 103-105 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-4-nitroanisole used for?
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2-Fluoro-4-nitroanisole is primarily used as an intermediate and building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and specialty materials. It allows for the introduction of specific fluorinated and nitrated aromatic structures into target molecules.
What is the CAS number and chemical formula for 2-Fluoro-4-nitroanisole?
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The CAS number is 455-93-6, and the chemical formula is FC6H3(NO2)OCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-4-nitroanisole with a purity of 98%. This is a technical grade suitable for research and synthesis; TSS does not represent it as USP, BP, or EP grade.
How should 2-Fluoro-4-nitroanisole be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (N95 recommended), eyeshields, and gloves. Avoid inhalation of dust and contact with skin and eyes. Ensure adequate ventilation. Refer to the Safety Data Sheet for full details. Hazards include skin irritation (H315), eye irritation (H319), and respiratory irritation (H335).
How is 2-Fluoro-4-nitroanisole packed, shipped, and exported?
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2-Fluoro-4-nitroanisole is carefully packed to maintain its integrity during transit. Tech Serve Solutions, a global supplier since 1998, handles export logistics efficiently to meet international shipping requirements.
How can I request a quote or sample for 2-Fluoro-4-nitroanisole?
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To request a quote or a sample of 2-Fluoro-4-nitroanisole, please contact our sales team through the website or by phone. Specify the product name and CAS number (455-93-6) in your inquiry.
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