2-Fluoro-4-methylpyridine
2-Fluoro-4-methylpyridine (CAS: 461-87-0), with the molecular formula C6H6FN and a molecular weight of 111.12 g/mol, is a fluorinated heterocyclic compound. It is valuable in organic synthesis, particularly as a building block for more complex molecules. This pyridine derivative is often employed in the development of new chemical entities and materials due to the unique properties imparted by the fluorine atom and the pyridine ring.
- IUPAC
- 2-Fluoro-4-picoline
- Synonyms
- 2-Fluoro-4-picoline

Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of diverse organic molecules. Its structure makes it suitable for introducing fluorinated pyridine moieties into larger compounds.
Pharmaceutical Research
Used in the discovery and development of novel pharmaceutical agents. The incorporation of fluoropyridine structures can influence the pharmacokinetic and pharmacodynamic properties of drug candidates.
Agrochemical Development
Can be utilised in the synthesis of new agrochemicals, such as pesticides and herbicides, where fluorinated heterocycles often exhibit enhanced biological activity.
Materials Science
Employed in the creation of functional materials, including those with specific electronic or optical properties, owing to the presence of the pyridine ring and fluorine substitution.
| Molecular weight | 111.12 |
|---|---|
| Empirical formula | C6H6FN |
| Assay | 98% |
| Boiling point | 160-161 °C(lit.) |
| Density | 1.078 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.472(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-4-methylpyridine used for?
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2-Fluoro-4-methylpyridine is primarily used as a building block in organic synthesis, particularly in the pharmaceutical, agrochemical, and materials science industries for developing new compounds.
What are the CAS number and formula for 2-Fluoro-4-methylpyridine?
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The CAS number is 461-87-0, and the molecular formula is C6H6FN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-4-methylpyridine with a minimum purity of 98%. This product is suitable for research and chemical synthesis and is not represented as USP, BP, or EP grade.
How should 2-Fluoro-4-methylpyridine be handled safely?
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Handle with care using appropriate personal protective equipment. It is classified as a skin, eye, and respiratory irritant (H315, H319, H335). Always consult the Safety Data Sheet (SDS) before use and ensure adequate ventilation.
Is 2-Fluoro-4-methylpyridine a controlled substance?
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The provided data does not indicate that 2-Fluoro-4-methylpyridine (CAS: 461-87-0) is a controlled substance.
How is 2-Fluoro-4-methylpyridine packed and shipped?
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Tech Serve Solutions professionally packs and exports fine chemicals globally, adhering to all relevant shipping regulations for hazardous materials.
How can I request a sample or quote for 2-Fluoro-4-methylpyridine?
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Please contact our sales team via the website or directly by phone to request a sample or a quotation for 2-Fluoro-4-methylpyridine.
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