2-Fluoro-5-(trifluoromethyl)aniline
2-Fluoro-5-(trifluoromethyl)aniline (CAS: 535-52-4) is a fluorinated aromatic amine with the chemical formula FC6H3(CF3)NH2 and a molecular weight of 179.11 g/mol. This compound serves as a valuable building block in organic synthesis. It is primarily utilised in research and development settings for the creation of more complex molecules, particularly within the pharmaceutical and agrochemical industries, owing to its specific structural features.
- IUPAC
- 3-Amino-4-fluorobenzotrifluoride,α,α,α,6-Tetrafluoro-m-toluidine
Chemical Synthesis
2-Fluoro-5-(trifluoromethyl)aniline is employed as an intermediate in the synthesis of various organic compounds. Its unique combination of a fluorine atom and a trifluoromethyl group makes it a useful precursor for developing novel chemical entities.
Pharmaceutical Research
This aniline derivative can be incorporated into the development of new pharmaceutical agents. The presence of fluorine and trifluoromethyl substituents can influence the pharmacokinetic and pharmacodynamic properties of drug candidates.
Agrochemical Development
The compound finds application in the design and synthesis of new agrochemicals. Its structural motifs are relevant for creating molecules with potential herbicidal, fungicidal, or insecticidal activity.
| Molecular weight | 179.11 |
|---|---|
| Linear formula | FC6H3(CF3)NH2 |
| Assay | 97% |
| Boiling point | 155 °C(lit.) |
| Density | 1.378 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.461(lit.) |
| Application | 2-Fluoro-5-(trifluoromethyl)aniline may be used in chemical synthesis studies. |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 70 °C / 158 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-5-(trifluoromethyl)aniline used for?
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2-Fluoro-5-(trifluoromethyl)aniline is primarily used as a building block in chemical synthesis, particularly for research and development in the pharmaceutical and agrochemical sectors.
What are the CAS number and chemical formula for this compound?
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The CAS number is 535-52-4, and the chemical formula is FC6H3(CF3)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-5-(trifluoromethyl)aniline with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 2-Fluoro-5-(trifluoromethyl)aniline be handled safely?
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This compound is classified under GHS07 with a Warning signal word. It has hazard statements H302, H312, H315, H319, H332, and H335, indicating it is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, is recommended.
Is 2-Fluoro-5-(trifluoromethyl)aniline exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Fluoro-5-(trifluoromethyl)aniline.
How can I request a quote or sample?
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To request a quote or sample of 2-Fluoro-5-(trifluoromethyl)aniline, please contact our sales team through the details provided on our website.
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