2,3,5,6-Tetrafluoropyridine
2,3,5,6-Tetrafluoropyridine (CAS: 2875-18-5), with the molecular formula C5HF4N and a molecular weight of 151.06 g/mol, is a fluorinated heterocyclic compound. It serves as a valuable building block in organic synthesis. Its unique fluorination pattern makes it useful in the development of novel materials and biologically active molecules within the pharmaceutical and agrochemical industries. Available in high purity, it is supplied by Tech Serve Solutions for research and development purposes.
- Synonyms
- 6-TetrafluoropyridineC5HF4N

Fluorinated Building Block
2,3,5,6-Tetrafluoropyridine is employed as a versatile synthon in organic chemistry. Its reactive nature allows for the introduction of fluorinated pyridine moieties into more complex molecular architectures, facilitating the synthesis of advanced materials and pharmaceuticals.
Pharmaceutical Intermediate
This compound serves as a key intermediate in the synthesis of various pharmaceutical agents. The presence of fluorine atoms can significantly influence the pharmacokinetic properties of drug candidates, such as metabolic stability and lipophilicity.
Agrochemical Development
It is utilised in the research and development of novel agrochemicals. Fluorinated heterocyclic compounds often exhibit enhanced biological activity and environmental persistence profiles, making them attractive for crop protection applications.
Materials Science
2,3,5,6-Tetrafluoropyridine finds application in materials science for the creation of functionalised polymers and organic electronic materials. Its specific electronic properties can be exploited to tune material characteristics.
| Molecular weight | 151.06 |
|---|---|
| Empirical formula | C5HF4N |
| Assay | 95% |
| Boiling point | 102 °C(lit.) |
| Density | 1.499 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4046(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 31 °C / 87.8 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 28-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,5,6-Tetrafluoropyridine used for?
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2,3,5,6-Tetrafluoropyridine is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and advanced materials due to its fluorinated heterocyclic structure.
What are the CAS number and formula for 2,3,5,6-Tetrafluoropyridine?
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The CAS number for 2,3,5,6-Tetrafluoropyridine is 2875-18-5, and its empirical formula is C5HF4N.
What grade and purity does Tech Serve Solutions supply for 2,3,5,6-Tetrafluoropyridine?
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Tech Serve Solutions supplies 2,3,5,6-Tetrafluoropyridine with a minimum assay of 95%. This product is intended for laboratory and research use and is not represented as USP, BP, or EP grade.
What are the main safety hazards associated with 2,3,5,6-Tetrafluoropyridine?
+
2,3,5,6-Tetrafluoropyridine is a flammable liquid and vapour (H226). It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including gloves, eyeshields, and respiratory protection, should be used when handling this chemical.
How is 2,3,5,6-Tetrafluoropyridine packed, shipped, and exported?
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2,3,5,6-Tetrafluoropyridine is carefully packed according to international shipping regulations for hazardous materials. As a global supplier, Tech Serve Solutions has extensive experience in exporting this chemical worldwide.
How can I request a sample or quote for 2,3,5,6-Tetrafluoropyridine?
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To request a sample or a quote for 2,3,5,6-Tetrafluoropyridine, please use the 'Request a Quote' or 'Sample Request' form on the Tech Serve Solutions website, or contact our sales team directly.
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