2,3,5,6-Tetrafluorobenzenethiol
2,3,5,6-Tetrafluorobenzenethiol (CAS: 769-40-4; Molecular Weight: 182.14 g/mol) is a fluorinated aromatic thiol supplied by Tech Serve Solutions. This compound serves as a valuable building block in organic synthesis, particularly for introducing fluorinated phenylthio moieties into more complex molecules. Its characteristic thiol group and tetrafluorinated phenyl ring make it a useful intermediate in the development of new materials and pharmaceuticals.
- IUPAC
- 2,3,5,6-Tetrafluorothiophenol
- Synonyms
- 6-TetrafluorobenzenethiolHC6F4SH2,3,5,6-Tetrafluorothiophenol

Fluorinated Building Block
Utilised as a key intermediate in organic synthesis to introduce fluorinated aromatic sulphur functionalities into target molecules. This is valuable in the development of novel pharmaceuticals and agrochemicals.
Material Science Intermediate
Its unique fluorinated structure can be incorporated into polymers or functional materials to impart specific properties, such as thermal stability or altered electronic characteristics.
Research and Development
A versatile reagent for laboratory-scale synthesis and exploratory research in areas requiring fluorinated organic compounds and sulphur-containing molecules.
| Molecular weight | 182.14 |
|---|---|
| Linear formula | HC6F4SH |
| Assay | 97% |
| Boiling point | 152-153 °C(lit.) |
| Refractive index | n20/D 1.4865(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 48 °C / 118.4 °F |
| Transport (UN / ADR) | UN 3336 3/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,5,6-Tetrafluorobenzenethiol primarily used for?
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2,3,5,6-Tetrafluorobenzenethiol is primarily used as a building block in organic synthesis for introducing fluorinated aromatic sulphur functionalities into target molecules, finding application in materials science and R&D.
What are the CAS number and molecular formula for 2,3,5,6-Tetrafluorobenzenethiol?
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The CAS number is 769-40-4, and the linear formula is HC6F4SH.
What grade and purity does Tech Serve Solutions supply for 2,3,5,6-Tetrafluorobenzenethiol?
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Tech Serve Solutions supplies 2,3,5,6-Tetrafluorobenzenethiol with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the key safety considerations when handling 2,3,5,6-Tetrafluorobenzenethiol?
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This compound is a flammable liquid and vapour (H226) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area.
How is 2,3,5,6-Tetrafluorobenzenethiol typically packed and shipped?
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2,3,5,6-Tetrafluorobenzenethiol is packed according to international regulations for hazardous materials and is exported globally by Tech Serve Solutions.
How can I request a sample or obtain a quote for 2,3,5,6-Tetrafluorobenzenethiol?
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To request a sample or obtain a quote, please contact our sales team through the website or by phone, providing your specific requirements.
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