2,3,5,6-Tetrafluorophenol
2,3,5,6-Tetrafluorophenol (CAS: 769-39-1; Formula: C6HF4OH) is a fluorinated organic compound with a molecular weight of 166.07 g/mol. This aryl building block features a phenol core with four fluorine substitutions, making it valuable in chemical synthesis. It is primarily utilised in the preparation of advanced intermediates for radiolabelled compounds used in peptide synthesis and the development of diagnostic agents.
- Synonyms
- 2,3,5,6-Tetrafluorophenol6-Tetrafluorophenol769-39-1HC6F4OH
Radiopharmaceutical Precursor
2,3,5,6-Tetrafluorophenol serves as a key intermediate in the synthesis of radioiodinated phenylalanine derivatives. These compounds are instrumental in developing radiotracers for Positron Emission Tomography (PET) imaging, particularly in peptide-based diagnostics.
Diagnostic Agent Development
This compound is employed in the preparation of technetium-99m labelled antibodies. Such radiolabelled antibodies are crucial in nuclear medicine for diagnostic imaging and targeted radiotherapy.
Fluorinated Building Block
As a versatile fluorinated building block, 2,3,5,6-Tetrafluorophenol is used in organic synthesis to introduce the tetrafluorophenyl moiety into more complex molecules, contributing to the development of novel materials and pharmaceuticals.
| Molecular weight | 166.07 |
|---|---|
| Linear formula | HC6F4OH |
| Assay | 97% |
| Boiling point | 140 °C(lit.) |
| Application | 2,3,5,6-Tetrafluorophenol was used in preparation of :• radioiodinated phenylalanine derivative which is useful in peptide synthesis1• technetium-99m labeled antibodies2 |
| Melting point | 37-39 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 79 °C / 174.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,5,6-Tetrafluorophenol used for?
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2,3,5,6-Tetrafluorophenol is primarily used as a building block in chemical synthesis, particularly for preparing intermediates for radiolabelled compounds such as radioiodinated phenylalanine derivatives and technetium-99m labelled antibodies.
What are the CAS number and molecular formula for 2,3,5,6-Tetrafluorophenol?
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The CAS number for 2,3,5,6-Tetrafluorophenol is 769-39-1, and its linear formula is C6HF4OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3,5,6-Tetrafluorophenol with an assay of 97%. This product is suitable for research and chemical synthesis purposes. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 2,3,5,6-Tetrafluorophenol be handled safely?
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2,3,5,6-Tetrafluorophenol is classified as a Warning substance (GHS07). It can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Ensure good ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes and seek medical advice.
Is 2,3,5,6-Tetrafluorophenol a controlled substance?
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Based on the provided data, there is no indication that 2,3,5,6-Tetrafluorophenol is a controlled substance.
How is 2,3,5,6-Tetrafluorophenol packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, adhering to all necessary regulations for safe packing and transportation. Specific packaging details are confirmed upon order placement.
How can I request a sample or quote for 2,3,5,6-Tetrafluorophenol?
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To request a sample or a quotation for 2,3,5,6-Tetrafluorophenol, please contact our sales department through the website or by direct inquiry, providing your specific requirements.
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