L-Homocysteine thiolactone hydrochloride
L-Homocysteine thiolactone hydrochloride (CAS: 31828-68-9), with the molecular formula C4H7NOS · HCl and a molecular weight of 153.63 g/mol, is a crucial homoserine derivative. This compound is primarily utilised in biochemical research and chemical synthesis. Its specific structure lends itself to applications in peptide chemistry and the study of modified amino acids, making it a valuable reagent for advancing scientific understanding in these fields.
- IUPAC
- L-2-Amino-4-mercaptobutyric acid 1,4-thiolactone hydrochloride

Peptide Synthesis
L-Homocysteine thiolactone hydrochloride serves as a building block in the synthesis of peptides. It allows for the introduction of non-canonical amino acid residues into peptide chains, enabling the exploration of novel peptide structures and functions.
Biochemical Research
This compound is employed in various biochemical studies, particularly those involving amino acid metabolism and protein modification. Its unique thiolactone ring structure offers a reactive intermediate for enzymatic or chemical investigations.
Chemical Biology
In chemical biology, L-Homocysteine thiolactone hydrochloride can be used as a tool to probe biological pathways or as a starting material for the synthesis of complex molecules with potential biological activity.
Organic Synthesis Intermediate
Its functional groups make it a versatile intermediate in organic synthesis for creating more complex heterocyclic compounds or modified amino acid derivatives.
| Molecular weight | 153.63 |
|---|---|
| Empirical formula | C4H7NOS · HCl |
| Assay | ≥99.0% (TLC) |
| Optical activity | [α]20/D +22.5±1°, c = 2.5% in 5 M HCl |
| Melting point | 185-191 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Homocysteine thiolactone hydrochloride used for?
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L-Homocysteine thiolactone hydrochloride is used in peptide synthesis, biochemical research, chemical biology, and as an intermediate in organic synthesis for creating modified amino acid derivatives and complex heterocyclic compounds.
What is the CAS number and formula for L-Homocysteine thiolactone hydrochloride?
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The CAS number is 31828-68-9, and the chemical formula is C4H7NOS · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Homocysteine thiolactone hydrochloride with an assay of ≥99.0% (TLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should L-Homocysteine thiolactone hydrochloride be handled?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, as it is classified under WGK Germany 3.
How is L-Homocysteine thiolactone hydrochloride shipped?
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L-Homocysteine thiolactone hydrochloride is carefully packed and exported by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical compounds.
How can I request a quote or sample?
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To request a quote or sample of L-Homocysteine thiolactone hydrochloride, please contact the Tech Serve Solutions sales team through our website or by phone.
Does L-Homocysteine thiolactone hydrochloride have any specific optical properties?
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Yes, it exhibits optical activity with [α]20/D +22.5±1°, measured at a concentration of 2.5% in 5 M HCl.
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