L-Homoserine
L-Homoserine (CAS: 672-15-1), with the linear formula HOCH2CH2CH(NH2)CO2H and a molecular weight of 119.12 g/mol, is a non-proteinogenic amino acid. It is an unnatural amino acid derivative and a biochemical reagent. L-Homoserine is primarily utilised in research settings, including chemical biology, peptide chemistry, and nutrition research, serving as a valuable building block in synthetic chemistry and biochemical studies.
- IUPAC
- (S)-2-Amino-4-hydroxybutyric acid,Hse
- Synonyms
- (S)-2-Amino-4-hydroxybutyric acidHse

Chemical Synthesis
L-Homoserine serves as a chiral building block in the synthesis of complex organic molecules and pharmaceutical intermediates. Its unique structure allows for the introduction of specific functionalities in advanced chemical preparations.
Biochemical Research
As a modified amino acid, L-Homoserine is employed in biochemical and cell biology research. It can be used to study protein structure, function, and metabolic pathways, particularly those involving amino acid derivatives.
Peptide Chemistry
In peptide chemistry, L-Homoserine can be incorporated into synthetic peptides to modify their properties or to investigate the effects of unnatural amino acids on peptide structure and biological activity.
Nutrition Research
This compound is utilised in nutrition research to explore metabolic processes and the role of non-essential amino acids. Its use helps in understanding nutritional requirements and biochemical pathways.
| Molecular weight | 119.12 |
|---|---|
| Linear formula | HOCH2CH2CH(NH2)CO2H |
| Assay | ≥98.0% (NT) |
| Optical activity | [α]20/D −9±1°, c = 2% in H2O |
| Loss on drying | ≤0.5% loss on drying |
| Melting point | 203 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Homoserine used for?
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L-Homoserine is used in chemical synthesis, biochemical research, peptide chemistry, and nutrition research. It acts as a non-proteinogenic amino acid building block for creating novel molecules and studying biological processes.
What is the CAS number and formula for L-Homoserine?
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The CAS number for L-Homoserine is 672-15-1, and its linear formula is HOCH2CH2CH(NH2)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Homoserine with an assay of ≥98.0% (NT). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should L-Homoserine be handled safely?
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When handling L-Homoserine, it is recommended to use safety precautions such as eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is advised. The compound has a melting point of 203 °C (dec.) and a WGK of 3 in Germany.
How is L-Homoserine packed and shipped?
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L-Homoserine is carefully packed and exported by Tech Serve Solutions, ensuring product integrity during transit. Specific packaging details are available upon request.
How can I request a sample or quote for L-Homoserine?
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To request a sample or quote for L-Homoserine, please contact the Tech Serve Solutions sales team through our website or by phone. Our experts will assist you promptly.
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