2-[(3′-(Trifluoromethyl)phenoxy)methyl]phenylboronic acid
2-[(3′-(Trifluoromethyl)phenoxy)methyl]phenylboronic acid (CAS: 1072951-60-0, C14H12BF3O3) is an organoboron compound with a molecular weight of 296.05 g/mol. It is a valuable building block in organic synthesis, primarily utilised in cross-coupling reactions like Suzuki-Miyaura coupling. Its trifluoromethylphenoxy substituent offers unique electronic and steric properties, making it a useful intermediate in the development of novel organic molecules, particularly in pharmaceutical and materials science research.
![2-[(3′-(Trifluoromethyl)phenoxy)methyl]phenylboronic acid (C14H12BF3O3) — chemical structure, CAS 1072951-60-0; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1072951-60-0.png&w=3840&q=75)
Suzuki-Miyaura Cross-Coupling Reactions
This phenylboronic acid derivative serves as a key coupling partner in Suzuki-Miyaura reactions. It enables the formation of carbon-carbon bonds, facilitating the synthesis of complex biaryl compounds and substituted aromatic systems.
Organic Synthesis Intermediate
It functions as a versatile intermediate in multi-step organic synthesis. The trifluoromethylphenoxy moiety and the boronic acid group provide distinct reactivity for introducing specific structural features into target molecules.
Materials Science
The compound can be employed in the development of novel organic materials, such as those for optoelectronic applications or functional polymers, where precise structural control is essential.
Pharmaceutical Research
Its structure is relevant for medicinal chemistry, serving as a building block for the synthesis of potential drug candidates and biologically active compounds.
| Molecular weight | 296.05 |
|---|---|
| Empirical formula | C14H12BF3O3 |
| Melting point | 97-101 °C |
Hazard statements
- H302Harmful if swallowed
- H413May cause long-lasting harmful effects to aquatic life
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-[(3′-(Trifluoromethyl)phenoxy)methyl]phenylboronic acid used for?
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2-[(3′-(Trifluoromethyl)phenoxy)methyl]phenylboronic acid is primarily used as a building block in organic synthesis, especially in Suzuki-Miyaura cross-coupling reactions, for creating complex organic molecules relevant to pharmaceutical research and materials science.
What is the CAS number and chemical formula for this compound?
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The CAS number is 1072951-60-0 and the chemical formula is C14H12BF3O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and laboratory use. The specific assay and grade are detailed in the product specifications. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should 2-[(3′-(Trifluoromethyl)phenoxy)methyl]phenylboronic acid be handled?
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This compound is classified as harmful if swallowed and may cause long-lasting harmful effects to aquatic life. Handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves. Avoid release into the environment.
Is this compound a controlled substance?
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Based on the provided data, there is no indication that 2-[(3′-(Trifluoromethyl)phenoxy)methyl]phenylboronic acid is a scheduled or controlled substance.
How is this chemical packed, shipped, and exported?
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This chemical is carefully packed to ensure safe transit and is available for export globally through Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for this product?
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To request a sample or a quotation, please contact our sales team through the website or by phone, providing the product name and CAS number.
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