2-[(3′,5′-Difluorophenoxy)methyl]phenylboronic acid
2-\[(3\',5\'-Difluorophenoxy)methyl\]phenylboronic acid (CAS: 1218790-92-1, C13H11BF2O3) is a sophisticated organoboron compound with a molecular weight of 264.03 g/mol. This aryl boronic acid derivative serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its unique difluorophenoxy substituent makes it an important intermediate for creating complex molecular architectures in pharmaceutical and materials science research.
- Synonyms
- C13H11BF2O3
![2-[(3′,5′-Difluorophenoxy)methyl]phenylboronic acid (C13H11BF2O3) — chemical structure, CAS 1218790-92-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1218790-92-1.png&w=3840&q=75)
Suzuki-Miyaura Cross-Coupling Reactions
This compound is extensively used as a coupling partner in Suzuki-Miyaura reactions, facilitating the formation of carbon-carbon bonds. It enables the synthesis of biaryl compounds and other complex organic molecules.
Pharmaceutical Intermediate Synthesis
Its structure lends itself to the development of novel pharmaceutical agents. It can be incorporated into drug discovery programs targeting various therapeutic areas.
Materials Science Research
The compound's unique electronic and structural properties make it suitable for the synthesis of advanced materials, including organic light-emitting diodes (OLEDs) and other functional organic materials.
Organic Synthesis Building Block
As a versatile organoboron reagent, it is employed in diverse synthetic strategies to introduce specific aryl or substituted aryl moieties into target molecules.
| Molecular weight | 264.03 |
|---|---|
| Empirical formula | C13H11BF2O3 |
| Melting point | 168-175 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-\[(3\',5\'-Difluorophenoxy)methyl\]phenylboronic acid used for?
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This compound is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for creating carbon-carbon bonds. It is also an important intermediate in the synthesis of pharmaceuticals and advanced materials.
What are the CAS number and formula for 2-\[(3\',5\'-Difluorophenoxy)methyl\]phenylboronic acid?
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The CAS number is 1218790-92-1 and the empirical formula is C13H11BF2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and development purposes. The specific grade and purity available are typically detailed in the product's specification sheet. It is not supplied as USP, BP, or EP grade.
How should 2-\[(3\',5\'-Difluorophenoxy)methyl\]phenylboronic acid be handled safely?
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This compound is a warning irritant. Handle with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Ensure adequate ventilation, avoid breathing dust, and prevent contact with skin and eyes. Refer to the Safety Data Sheet (SDS) for comprehensive handling information.
Is 2-\[(3\',5\'-Difluorophenoxy)methyl\]phenylboronic acid a controlled substance?
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Based on the provided data, there is no indication that this compound is a controlled substance.
How is 2-\[(3\',5\'-Difluorophenoxy)methyl\]phenylboronic acid packed and shipped?
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Tech Serve Solutions professionally packs and exports chemicals globally, adhering to international shipping regulations for hazardous materials to ensure safe and compliant delivery.
How can I request a sample or quote for 2-\[(3\',5\'-Difluorophenoxy)methyl\]phenylboronic acid?
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To request a sample or a quotation, please contact our sales team through the website or by calling our office. Provide the product name and CAS number for prompt assistance.
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