L-Histidinol dihydrochloride
L-Histidinol dihydrochloride (CAS: 1596-64-1), with the chemical formula C6H11N3O · 2HCl and a molecular weight of 214.09 g/mol, is a derivative of the amino acid histidine. This compound serves as a valuable building block and intermediate in chemical synthesis, particularly within the fields of peptide chemistry and chemical biology. Its defined stereochemistry and functional groups make it useful for research and development purposes in various scientific disciplines.
- IUPAC
- β-Aminoimidazole-4-propanol dihydrochloride,(S)-2-Amino-3-(4-imidazolyl)propanol dihydrochloride

Peptide Synthesis
L-Histidinol dihydrochloride can be employed as a modified amino acid derivative in the synthesis of peptides, enabling the introduction of specific structural features or functionalities. Its incorporation can influence peptide conformation and biological activity.
Chemical Biology Research
As a biologically relevant molecule, it finds application in studies within chemical biology, potentially serving as a probe or tool compound to investigate biochemical pathways or enzyme mechanisms. Its role as an amino alcohol derivative is of particular interest.
Organic Synthesis Intermediate
This compound acts as a versatile intermediate in organic synthesis for creating more complex molecules. Researchers can leverage its chiral center and reactive functional groups for various synthetic transformations.
| Molecular weight | 214.09 |
|---|---|
| Empirical formula | C6H11N3O · 2HCl |
| Assay | ≥99.0% (AT) |
| Optical activity | [α]20/D −2.8±0.5°, c = 2% in H2O |
| Melting point | ~195 °C (dec.)198-201 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Histidinol dihydrochloride used for?
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L-Histidinol dihydrochloride is primarily used as an intermediate in chemical synthesis, particularly in peptide chemistry and chemical biology research. It serves as a building block for creating more complex molecules and for investigating biological processes.
What is the CAS number and formula for L-Histidinol dihydrochloride?
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The CAS number for L-Histidinol dihydrochloride is 1596-64-1, and its chemical formula is C6H11N3O · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Histidinol dihydrochloride with an assay of ≥99.0% (AT). This is a technical/research grade, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeial grade.
What are the safety considerations when handling L-Histidinol dihydrochloride?
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L-Histidinol dihydrochloride is classified as a Warning substance with hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Ensure adequate ventilation.
How is L-Histidinol dihydrochloride packed, shipped, and exported?
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L-Histidinol dihydrochloride is carefully packed for safe transit and exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical compounds.
How can I request a sample or quote for L-Histidinol dihydrochloride?
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To request a sample or a quote for L-Histidinol dihydrochloride, please contact our sales team through the website or by phone, providing your specific requirements.
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