L-Histidine
L-Histidine (CAS: 71-00-1), a vital alpha-amino acid with the molecular formula C6H9N3O2 and a molecular weight of 155.15 g/mol, is supplied by TSS. Available as a white powder, it is sourced from non-animal origins. L-Histidine serves as a fundamental building block in protein synthesis and plays a role in various biological processes, making it a key compound in biochemical research and synthesis applications.
- IUPAC
- (S)-2-Amino-3-(4-imidazolyl)propionic acid,NSC 137773

Biochemical Research
L-Histidine is widely utilised in biochemical studies to investigate protein structure and function, enzyme mechanisms, and cellular signalling pathways. Its unique imidazole side chain contributes to its catalytic activity and buffering capabilities.
Chemical Synthesis
This amino acid derivative serves as a valuable chiral building block in the synthesis of complex organic molecules and pharmaceutical intermediates. It is incorporated into peptides and peptidomimetics for drug discovery efforts.
Cell Biology Studies
In cell biology, L-Histidine is used in cell culture media to support cell growth and metabolism. It is also employed in studies related to histidine metabolism and its impact on cellular health.
Analytical Standards
With a high purity of ≥99.0% (NT), L-Histidine can function as a reference standard in analytical chemistry, particularly in chromatography and spectroscopy for the identification and quantification of related compounds.
| Molecular weight | 155.15 |
|---|---|
| Empirical formula | C6H9N3O2 |
| Assay | ≥99.0% (NT) |
| Form | powder |
| Optical activity | [α]20/D −39±1°, c = 2% in H2O |
| Loss on drying | ≤0.5% loss on drying, 110 °C |
| Impurities tested | ≤0.5% foreign amino acids |
| Melting point | 282 °C (dec.)(lit.)~285 °C (dec.) |
| Biological source | from non-animal source |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 1 |
| Cation traces | Ca: ≤10 mg/kgCd: ≤5 mg/kgCo: ≤5 mg/kgCr: ≤5 mg/kgCu: ≤5 mg/kgFe: ≤5 mg/kgK: ≤50 mg/kgMg: ≤5 mg/kgMn: ≤5 mg/kgNH4+: ≤500 mg/kgNa: ≤50 mg/kgNi: ≤5 mg/kgPb: ≤5 mg/kgZn: ≤5 mg/kg |
| Anion traces | chloride (Cl-): ≤100 mg/kgsulfate (SO42-): ≤100 mg/kg |
| Ignition residue | ≤0.1% (as SO4) |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CA1(759), CA2(760) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Histidine used for?
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L-Histidine is used in biochemical research, chemical synthesis, cell biology studies, and as an analytical standard. It is a fundamental building block in protein synthesis and plays roles in biological processes.
What is the CAS number and molecular formula for L-Histidine?
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The CAS number for L-Histidine is 71-00-1, and its molecular formula is C6H9N3O2.
What grade and purity does Tech Serve Solutions supply for L-Histidine?
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Tech Serve Solutions supplies L-Histidine with an assay of ≥99.0% (NT). This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should L-Histidine be handled safely?
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Handle L-Histidine with appropriate personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Refer to the Safety Data Sheet for detailed handling instructions.
How is L-Histidine packed and exported by TSS?
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L-Histidine is supplied as a powder and is available for domestic and international export by Tech Serve Solutions.
How can I request a quote or sample of L-Histidine?
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To request a quote or a sample of L-Histidine, please contact the Tech Serve Solutions sales team through our website or by phone.
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