2,6-Bis[(4S,5S)-4-methyl-5-phenyl-2-oxazolinyl]pyridine
2,6-Bis[(4S,5S)-4-methyl-5-phenyl-2-oxazolinyl]pyridine (CAS: 185346-20-7) is a chiral ligand with a molecular weight of 397.47 g/mol. This compound is primarily utilised in asymmetric synthesis as a valuable chiral catalyst and ligand. Its well-defined stereochemistry makes it instrumental in directing enantioselective reactions, contributing to the development of complex chiral molecules.
- IUPAC
- 2,6-Bis[(4S,5S)-4,5-dihydro-4-methyl-5-phenyl-2-oxazolyl]pyridine
- Synonyms
- 185346-20-7C25H23N3O22,6-Bis[(4S,5S)-4,5-dihydro-4-methyl-5-phenyl-2-oxazolyl]pyridine
![2,6-Bis[(4S,5S)-4-methyl-5-phenyl-2-oxazolinyl]pyridine (C25H23N3O2) — chemical structure, CAS 185346-20-7; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F185346-20-7.png&w=3840&q=75)
Chiral Ligand in Asymmetric Synthesis
Serves as a crucial chiral ligand in transition metal-catalyzed asymmetric reactions. It facilitates the enantioselective formation of chiral products, essential in pharmaceutical and fine chemical synthesis.
Catalysis Research
Investigated for its efficacy in various asymmetric transformations, including cyclopropanation, hydrosilylation, and Diels-Alder reactions, enabling precise stereochemical control.
Development of Privileged Structures
Contributes to the synthesis of complex molecules containing stereocenters, often employed in medicinal chemistry and the discovery of new bioactive compounds.
| Molecular weight | 397.47 |
|---|---|
| Empirical formula | C25H23N3O2 |
| Assay | 98% |
| Optical activity | [α]22/D −132°, c = 1 in chloroform |
| Melting point | 138-141 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,6-Bis[(4S,5S)-4-methyl-5-phenyl-2-oxazolinyl]pyridine used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis to direct enantioselective reactions and in catalysis research.
What are the CAS number and formula for this product?
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The CAS number is 185346-20-7 and the empirical formula is C25H23N3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 98%. We do not represent it as USP, BP, or EP grade.
How should 2,6-Bis[(4S,5S)-4-methyl-5-phenyl-2-oxazolinyl]pyridine be handled?
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Handle with appropriate personal protective equipment, including a dust mask (N95 type), eyeshields, and gloves. Avoid dust formation and breathing. Use only in a well-ventilated area. It is classified as causing skin irritation, serious eye irritation, and respiratory irritation.
Is this chemical shipped internationally?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or quote?
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Please contact our sales team through the website or by phone to request a sample or a formal quotation.
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