2,6-Di-tert-butyl-4-methoxyphenol
2,6-Di-tert-butyl-4-methoxyphenol (CAS 489-01-0) is a sterically hindered phenol with the molecular formula C15H24O2 and a molar mass of 236.35 g/mol. This compound functions as an effective antioxidant, finding application in the protection of cosmetics, pharmaceuticals, and foodstuffs against oxidative degradation. Its specific chemical structure contributes to its stability and efficacy in preventing spoilage and extending product shelf-life.
- IUPAC
- 3,5-Di-tert-butyl-4-hydroxyanisole
- Synonyms
- 3,5-Di-tert-butyl-4-hydroxyanisole4-Methoxy-2,6-di-tert-butylphenol
![2,6-Di-tert-butyl-4-methoxyphenol (CH3OC6H2[C(CH3)3]2OH) — chemical structure, CAS 489-01-0; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F489-01-0.png&w=3840&q=75)
Antioxidant for Cosmetics
This compound serves as an antioxidant in cosmetic formulations, safeguarding products from oxidation and extending their stability. It helps to preserve the integrity of ingredients and maintain product quality over time.
Stabiliser in Pharmaceuticals
2,6-Di-tert-butyl-4-methoxyphenol is utilised in pharmaceutical applications to prevent oxidative degradation of active pharmaceutical ingredients and excipients. This ensures the efficacy and shelf-life of medicinal products.
Foodstuff Protection
The compound acts as an antioxidant in various food products, preventing rancidity and preserving freshness. Its inclusion helps to maintain the organoleptic properties and nutritional value of food items.
Chemical Synthesis Intermediate
As a building block, it can be employed in organic synthesis for the creation of more complex molecules. Its sterically hindered phenolic structure offers unique reactivity and stability in synthetic pathways.
| Molecular weight | 236.35 |
|---|---|
| Linear formula | CH3OC6H2[C(CH3)3]2OH |
| Assay | 97% |
| Application | 2,6-Di-tert-butyl-4-methoxyphenol has been used to protect cosmetics, drugs and foods from oxidative degradation1. |
| Melting point | 102-106 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,6-Di-tert-butyl-4-methoxyphenol used for?
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2,6-Di-tert-butyl-4-methoxyphenol is used to protect cosmetics, drugs, and foods from oxidative degradation. It functions as a versatile antioxidant and building block in chemical synthesis.
What are the CAS number and chemical formula for 2,6-Di-tert-butyl-4-methoxyphenol?
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The CAS number for 2,6-Di-tert-butyl-4-methoxyphenol is 489-01-0, and its linear formula is CH3OC6H2[C(CH3)3]2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,6-Di-tert-butyl-4-methoxyphenol with an assay of 97%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and general chemical applications.
How should 2,6-Di-tert-butyl-4-methoxyphenol be handled safely?
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Handling requires appropriate personal protective equipment, including a dust mask (N95 US type), eyeshields, and gloves. Avoid inhalation of dust and contact with skin and eyes. The compound is classified as a skin irritant (H315), eye irritant (H319), and respiratory irritant (H335).
How is this chemical packed and shipped?
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2,6-Di-tert-butyl-4-methoxyphenol is packed according to industry standards for chemical safety and stability. TSS exports globally; please contact us for specific shipping and handling details for your region.
How can I request a sample or quote?
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To request a sample or a quotation for 2,6-Di-tert-butyl-4-methoxyphenol, please use the contact form on our website or call our sales department directly.
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