2,6-Di-tert-butylpyridine
2,6-Di-tert-butylpyridine (CAS 585-48-8), a pyridine derivative with the molecular formula C13H21N and a molecular weight of 191.31 g/mol, is a sterically hindered organic compound. Its unique structure makes it an effective proton trapping agent in polymerization studies and a valuable reagent in organic synthesis, particularly in reactions involving enolates. Supplied by Tech Serve Solutions with an assay of ≥97%, it serves as a key building block in chemical research and development.
- Synonyms
- 2,6-bis(1,1-dimethylethyl)pyridine2,6-di-tert-butylpyridine
Proton Trapping Agent
2,6-Di-tert-butylpyridine is utilised as a proton trapping agent. This application is demonstrated in the investigation of the living polymerization of isobutylene, where its steric hindrance effectively moderates proton activity.
Organic Synthesis Reagent
This compound serves as a reagent in organic synthesis, notably in conjunction with cerric ammonium nitrate. It facilitates the alpha-enolation of aldehydes, leading to the formation of 1,4-dicarbonyl systems.
Sterically Hindered Base
Due to its bulky tert-butyl groups adjacent to the nitrogen atom, 2,6-Di-tert-butylpyridine functions as a non-nucleophilic, sterically hindered base in various chemical reactions, selectively abstracting protons without interfering with electrophilic centres.
| Molecular weight | 191.31 |
|---|---|
| Empirical formula | C13H21N |
| Assay | ≥97% |
| Boiling point | 100-101 °C/23 mmHg(lit.) |
| Density | 0.852 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.473(lit.) |
| Storage temperature | 2-8°C |
| Application | 2,6-Di-tert-butylpyridine was used as proton trapping agent to investigate the living polymerization of isobutylene1. It was also used with cerric ammonium nitrate in the α-enolation of aldehydes leading to 1,4-dicarbonyl systems2. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 71 °C / 159.8 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,6-Di-tert-butylpyridine primarily used for?
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2,6-Di-tert-butylpyridine is primarily used as a proton trapping agent in polymerization studies and as a reagent in organic synthesis, particularly for alpha-enolation of aldehydes.
What are the CAS number and formula for 2,6-Di-tert-butylpyridine?
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The CAS number for 2,6-Di-tert-butylpyridine is 585-48-8, and its molecular formula is C13H21N.
What grade and purity does Tech Serve Solutions supply for 2,6-Di-tert-butylpyridine?
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Tech Serve Solutions supplies 2,6-Di-tert-butylpyridine with an assay of ≥97%. This product is suitable for research and general laboratory use; TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
How should 2,6-Di-tert-butylpyridine be handled safely?
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2,6-Di-tert-butylpyridine is a warning hazard and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It is recommended to wear eyeshields, gloves, and use appropriate respiratory protection, such as a multi-purpose combination respirator cartridge, in a well-ventilated area. Store at 2-8°C.
How is 2,6-Di-tert-butylpyridine packed and shipped?
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2,6-Di-tert-butylpyridine is packed securely according to industry standards for chemical transport and can be exported globally by Tech Serve Solutions. Specific packaging details will be provided with your order.
How can I request a sample or quote for 2,6-Di-tert-butylpyridine?
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To request a sample or quote for 2,6-Di-tert-butylpyridine, please contact our sales team through the website or by direct inquiry, providing your contact details and the quantity required.
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