2,6-Bis[(4R)-4-phenyl-2-oxazolinyl]pyridine
2,6-Bis[(4R)-4-phenyl-2-oxazolinyl]pyridine (CAS: 128249-70-7) is a chiral pyridine-based bis(oxazoline) ligand with a molecular weight of 369.42 g/mol. This compound is primarily utilised as a highly effective chiral auxiliary and catalyst in asymmetric synthesis. It plays a crucial role in stereoselective transformations, enabling the production of enantiomerically enriched molecules for various advanced chemical applications.
- IUPAC
- (R,R)-2,6-Bis(4,5-dihydro-4-phenyl-2-oxazolyl)pyridine,(R,R)-2,6-Bis(4-phenyl-2-oxazolinyl)pyridine
- Synonyms
- (R,R)-2,6-Bis(4,5-dihydro-4-phenyl-2-oxazolyl)pyridine(R,R)-2,6-Bis(4-phenyl-2-oxazolinyl)pyridine
![2,6-Bis[(4R)-4-phenyl-2-oxazolinyl]pyridine (C23H19N3O2) — chemical structure, CAS 128249-70-7; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F128249-70-7.png&w=3840&q=75)
Chiral Ligand in Asymmetric Catalysis
Serves as a privileged ligand in metal-catalyzed asymmetric reactions, facilitating enantioselective bond formations. Its rigid structure and specific stereochemistry allow for high levels of stereocontrol in a variety of transformations.
Asymmetric Synthesis
Essential reagent for introducing chirality in organic synthesis. It is employed in reactions such as asymmetric cyclopropanation, allylic alkylation, and Diels-Alder reactions, leading to the formation of chiral products.
Lewis Acid Catalysis
Forms active chiral Lewis acid complexes when coordinated with various metal centres. These complexes are vital for promoting stereoselective reactions that are difficult to achieve with achiral catalysts.
| Molecular weight | 369.42 |
|---|---|
| Empirical formula | C23H19N3O2 |
| Assay | 98% |
| Optical activity | [α]22/D 187°, c = 1 in methylene chloride |
| Melting point | 171-175 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,6-Bis[(4R)-4-phenyl-2-oxazolinyl]pyridine used for?
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It is primarily used as a chiral ligand in asymmetric catalysis and as a chiral auxiliary in asymmetric synthesis to produce enantiomerically enriched molecules.
What are the CAS number and formula for this compound?
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The CAS number is 128249-70-7 and the empirical formula is C23H19N3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 98%. We do not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should this chemical be handled safely?
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This compound is a warning irritant to skin, eyes, and respiratory tract. Handle with appropriate personal protective equipment including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure adequate ventilation.
How are your chemicals packed and exported?
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Tech Serve Solutions expertly packs and exports fine chemicals globally, adhering to all necessary international shipping regulations for hazardous materials.
How can I request a sample or quote?
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To request a sample or quote, please contact our sales team via the website or by phone, providing the product name and CAS number (128249-70-7).
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