2,6-Bis(trifluoromethyl)pyridine
2,6-Bis(trifluoromethyl)pyridine (CAS 455-00-5) is a fluorinated pyridine derivative with the molecular formula C7H3F6N and a molecular weight of 215.10 g/mol. This compound is characterised by the presence of two trifluoromethyl groups on the pyridine ring, making it a valuable building block in organic synthesis. It finds application in the preparation of complex molecules, particularly within the pharmaceutical and agrochemical industries, owing to the unique electronic and steric properties imparted by the trifluoromethyl substituents.
- Synonyms
- C7H3F6N

Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of novel organic compounds. Its trifluoromethyl groups can influence reactivity and molecular properties, making it useful for creating specialised chemical structures.
Pharmaceutical Research
Utilised in medicinal chemistry for the development of potential drug candidates. The incorporation of fluorinated pyridine motifs can enhance metabolic stability and bioavailability of pharmaceutical agents.
Agrochemical Development
Employed in the design and synthesis of new agrochemicals. Fluorinated compounds often exhibit desirable biological activity, and this pyridine derivative can be incorporated into novel pesticides or herbicides.
Material Science
Potentially used in the development of advanced materials where fluorinated organic molecules are required to achieve specific electronic or physical properties.
| Molecular weight | 215.10 |
|---|---|
| Empirical formula | C7H3F6N |
| Assay | 97% |
| Boiling point | 82 °C/18 mmHg |
| Melting point | 55-59 °C |


Hazard statements
- H228Flammable solid
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 67 °C / 152.6 °F |
| Transport (UN / ADR) | UN 2926 4.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,T |
| Risk statements (R) | 11-25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,6-Bis(trifluoromethyl)pyridine used for?
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2,6-Bis(trifluoromethyl)pyridine is primarily used as a building block and intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals.
What is the CAS number and molecular formula for 2,6-Bis(trifluoromethyl)pyridine?
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The CAS number for 2,6-Bis(trifluoromethyl)pyridine is 455-00-5, and its molecular formula is C7H3F6N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,6-Bis(trifluoromethyl)pyridine with a minimum assay of 97%. This is a technical or research grade material, and TSS does not represent it as USP, BP, or EP grade.
How should 2,6-Bis(trifluoromethyl)pyridine be handled safely?
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Handling requires strict safety precautions due to its flammability (flash point 67 °C) and toxicity (H228-H301-H315-H319-H335). Use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, and work in a well-ventilated area away from ignition sources.
How is 2,6-Bis(trifluoromethyl)pyridine packed and shipped?
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This product is packed and shipped according to international regulations for hazardous materials (UN 2926, Hazard Class 4.1). TSS ensures compliance for global export.
How can I request a sample or quote for 2,6-Bis(trifluoromethyl)pyridine?
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To request a sample or quote, please contact our sales department via the website or by calling the provided telephone number, specifying the product name and CAS number.
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