2,6-Bis[(4R)-(+)-isopropyl-2-oxazolin-2-yl]pyridine
2,6-Bis[(4R)-(+)-isopropyl-2-oxazolin-2-yl]pyridine (CAS: 131864-67-0) is a chiral C2-symmetric bidentate ligand. Its strong affinity for metals facilitates the formation of coordination complexes, making it highly valuable in enantioselective catalysis. Available at 99% purity, this compound is a key reagent for asymmetric synthesis and chemical transformations requiring precise stereochemical control.
- Synonyms
- C17H23N3O2
![2,6-Bis[(4R)-(+)-isopropyl-2-oxazolin-2-yl]pyridine (C17H23N3O2) — chemical structure, CAS 131864-67-0; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F131864-67-0.png&w=3840&q=75)
Enantioselective Catalysis
This C2-symmetric bidentate ligand is extensively used in asymmetric synthesis. It readily forms stable coordination complexes with various transition metals, enabling highly enantioselective catalytic reactions.
Chiral Catalyst Development
The molecule's structure allows for precise stereochemical control in catalytic processes. It serves as a fundamental building block for developing advanced chiral catalysts used in complex organic synthesis.
Ligand Synthesis
As a pyridine-based bis(oxazoline) ligand, it is a significant component in the synthesis of privileged ligands and their metal complexes, finding broad utility in catalysis research.
| Molecular weight | 301.38 |
|---|---|
| Empirical formula | C17H23N3O2 |
| Assay | 99% |
| Optical activity | [α]20/D +118°, c = 0.7 in methylene chloride |
| Application | C2 symmetric ligand for enantioselective catalysis. Easily forms bidentate coordination complexes due to the strong affinity of the oxazoline nitrogen for various metals.1,2,3 |
| Melting point | 154-156 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,6-Bis[(4R)-(+)-isopropyl-2-oxazolin-2-yl]pyridine used for?
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This compound is primarily used as a chiral C2-symmetric bidentate ligand for enantioselective catalysis. It is valuable in asymmetric synthesis and the development of chiral catalysts due to its strong affinity for metals and ability to form coordination complexes.
What is the CAS number and molecular formula for this compound?
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The CAS number is 131864-67-0 and the empirical formula is C17H23N3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,6-Bis[(4R)-(+)-isopropyl-2-oxazolin-2-yl]pyridine with an assay of 99%. This is a research-grade chemical and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should this chemical be handled safely?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be worn. Handle in a well-ventilated area.
Is this chemical a controlled substance?
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The provided data does not indicate that this chemical is a controlled substance.
How is this product packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports fine chemicals globally, adhering to all relevant regulations for safe and secure transport.
How can I request a sample or a quote?
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To request a sample or a quote for 2,6-Bis[(4R)-(+)-isopropyl-2-oxazolin-2-yl]pyridine, please contact our sales team through the website or by phone.
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