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Trimethyl(phenoxy)silane

CAS 1529-17-5C6H5OSi(CH3)3Chemical Synthesis

Trimethyl(phenoxy)silane (CAS: 1529-17-5), with the molecular formula C6H5OSi(CH3)3 and a molecular weight of 166.29 g/mol, is a valuable organic building block. It serves as a protecting group for phenols and finds application in organic synthesis. Its primary role is in facilitating complex chemical transformations through its unique silyl ether functionality.

IUPAC
Phenoxy(trimethyl)silane,Phenyl trimethylsilyl ether
Synonyms
Phenoxy(trimethyl)silanePhenyl trimethylsilyl ether
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Trimethyl(phenoxy)silane (C6H5OSi(CH3)3) — chemical structure, CAS 1529-17-5; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisOrganic Building BlocksOxygen CompoundsProtected Alcohols/Phenols
01 /Applications

Phenol Protection

Trimethyl(phenoxy)silane is commonly employed as a silylating agent to protect hydroxyl groups in phenols. This protection strategy is crucial in multi-step organic syntheses, preventing unwanted side reactions of the phenolic hydroxyl during other transformations.

Organic Synthesis Intermediate

As a versatile building block, this compound participates in various organic reactions. It contributes to the construction of more complex molecular architectures, making it a useful reagent in academic research and industrial chemical development.

Research and Development

Its specific chemical properties make it a reagent of interest in laboratories exploring novel synthetic routes and chemical methodologies. It aids in the development of new materials and pharmaceutical intermediates.

02 /Properties
Molecular weight166.29
Linear formulaC6H5OSi(CH3)3
Assay97%
Density0.92 g/mL at 25 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H226Flammable liquid and vapour
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point41 °C / 105.8 °F
Transport (UN / ADR)UN 1993C 3 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)10-36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
1529-17-5
MDL number
MFCD00053666
PubChem substance
24863740
Beilstein registry
1905943
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Trimethyl(phenoxy)silane used for?

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Trimethyl(phenoxy)silane is primarily used as a protecting group for phenols in organic synthesis and as a general building block for creating more complex molecules.

What are the CAS number and formula for Trimethyl(phenoxy)silane?

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The CAS number for Trimethyl(phenoxy)silane is 1529-17-5, and its linear formula is C6H5OSi(CH3)3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Trimethyl(phenoxy)silane with an assay of 97%. This is a technical grade, and TSS does not represent it as USP, BP, or EP grade.

How should Trimethyl(phenoxy)silane be handled safely?

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Trimethyl(phenoxy)silane is a flammable liquid and vapour (H226) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area.

How is Trimethyl(phenoxy)silane packaged and shipped?

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Trimethyl(phenoxy)silane is shipped as a UN 1993, Class 3, Packing Group III hazardous material. TSS ensures compliant packaging and export procedures for this chemical.

How can I request a sample or quote for Trimethyl(phenoxy)silane?

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To request a sample or a quote for Trimethyl(phenoxy)silane, please contact the TSS sales team through our website or direct inquiry channels.

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