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Trimethyl phosphonoacetate

CAS 5927-18-4(CH3O)2P(O)CH2CO2CH3Chemical Synthesis

Trimethyl phosphonoacetate (CAS 5927-18-4), molecular formula (CH3O)2P(O)CH2CO2CH3, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.

IUPAC
(Carboxymethyl)phosphonic acid trimethyl ester,NSC 84262
Trimethyl phosphonoacetate
C-C Bond FormationChemical SynthesisOlefinationSynthetic Reagents
01 /Properties
Molecular weight182.11
Linear formula(CH3O)2P(O)CH2CO2CH3
Assay≥98.0% (GC)
Boiling point118 °C/0.85 mmHg(lit.)265-268 °C(lit.)
Density1.125 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.437(lit.)n20/D 1.437
ApplicationReactant involved in:• Intramolecular Mannich-type reactions to produce the sarain A diazatricyclic core1• Organocatalytic oxa-Michael reactions2• Prenylation and geranylation of oxindoles3• Intramolecular Horner-Wadsworth-Emmons reactions4,5• Olefin cross-metathesis / heterocyclization6
02 /Safety & handling
Protective equipmentEyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point113 °C / 235.4 °F
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

03 /Identifiers & registry
CAS number
5927-18-4
MDL number
MFCD00008452
PubChem substance
24900489
Beilstein registry
1865177
04 /Quality & supply

Documentation

Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is Trimethyl phosphonoacetate?

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Trimethyl phosphonoacetate (CAS 5927-18-4), molecular formula (CH3O)2P(O)CH2CO2CH3, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.

What grades of Trimethyl phosphonoacetate does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Trimethyl phosphonoacetate in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.

What is the CAS number and molecular formula of Trimethyl phosphonoacetate?

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Trimethyl phosphonoacetate has CAS number 5927-18-4 and molecular formula (CH3O)2P(O)CH2CO2CH3. Full specifications appear in the table above and in the Certificate of Analysis.

What is the typical minimum order quantity and lead time for Trimethyl phosphonoacetate?

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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.

Do you provide a Certificate of Analysis (CoA) with each shipment?

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Yes. Every batch of Trimethyl phosphonoacetate ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.

How should Trimethyl phosphonoacetate be stored?

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Store Trimethyl phosphonoacetate in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.

What is Trimethyl phosphonoacetate used for?

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Trimethyl phosphonoacetate is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.

How do I request a quote for Trimethyl phosphonoacetate?

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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.

Need Trimethyl phosphonoacetate in a specific grade or volume?

Request a quote