Octadecylsilane
Octadecylsilane (CAS 18623-11-5), with the chemical formula CH3(CH2)17SiH3 and a molecular weight of 284.60 g/mol, is an organosilicon compound. It is primarily utilised as a derivatisation reagent in gas chromatography and as a stationary phase component in liquid chromatography for separating non-polar and weakly polar compounds. Its amphiphilic nature makes it suitable for creating hydrophobic surfaces.

Gas Chromatography Derivatisation
Octadecylsilane can be used to derivatise analytes, rendering them more volatile and thermally stable for improved separation and detection in gas chromatography.
Chromatographic Stationary Phases
It serves as a key component in the preparation of stationary phases for both gas and liquid chromatography, particularly for reversed-phase applications involving non-polar analytes.
Surface Modification
The compound can be employed to modify surfaces, introducing long hydrophobic alkyl chains to create water-repellent or non-stick coatings.
Chemical Synthesis
Octadecylsilane acts as a versatile building block in organosilicon chemistry and organic synthesis, enabling the introduction of long alkyl chains with a reactive silane group.
| Molecular weight | 284.60 |
|---|---|
| Linear formula | CH3(CH2)17SiH3 |
| Assay | 97% |
| Boiling point | 195 °C/15 mmHg(lit.) |
| Density | 0.795 g/mL at 25 °C(lit.) |
| Melting point | 29 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | 110 °C / 230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Octadecylsilane used for?
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Octadecylsilane (CAS 18623-11-5) is used as a derivatisation reagent in gas chromatography, as a component in chromatographic stationary phases, and for surface modification to introduce hydrophobic properties.
What are the CAS number and formula for Octadecylsilane?
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The CAS number for Octadecylsilane is 18623-11-5 and its linear formula is CH3(CH2)17SiH3.
What grade and purity does Tech Serve Solutions supply for Octadecylsilane?
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Tech Serve Solutions supplies Octadecylsilane with an assay of 97%. We do not represent this product as meeting USP, BP, EP, or any other pharmacopoeia standards.
What are the safety and handling recommendations for Octadecylsilane?
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Octadecylsilane is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, ensuring good ventilation, and avoid contact with skin, eyes, and clothing. Follow P261 and P305 + P351 + P338 precautionary statements.
How is Octadecylsilane packed, shipped, and exported by TSS?
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Tech Serve Solutions professionally packs, handles, and exports chemicals globally, adhering to all relevant shipping regulations to ensure safe and timely delivery to your laboratory or facility.
How can I request a quote or sample for Octadecylsilane?
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To request a quote or a sample of Octadecylsilane, please contact our sales team through the website or call us directly. We are happy to assist with your chemical needs.
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