Trimethyl orthoformate
Trimethyl orthoformate (CAS: 149-73-5), with the molecular formula CH(OCH3)3 and a molar mass of 106.12 g/mol, is a vital organic compound. It functions as a dehydrating agent and is widely employed in chemical synthesis. Its applications span various laboratory and industrial processes, serving as a versatile building block in organic chemistry. This ester offers reliable performance in reactions requiring the removal of water.
- IUPAC
- Trimethoxymethane
- Synonyms
- Trimethoxymethane
Dehydrating Agent in Nanoparticle Synthesis
Trimethyl orthoformate serves as an effective dehydrating agent in the preparation of surface-modified colloidal silica nanoparticles. Its ability to remove water drives the synthesis process for these advanced materials.
Chemical Synthesis Intermediate
As an organic building block, Trimethyl orthoformate is utilised in various chemical synthesis pathways. It is a valuable reagent for introducing specific functional groups or facilitating transformations in organic chemistry.
Orthoester Chemistry
This compound belongs to the class of orthoesters, making it a useful precursor or reagent in reactions involving acetal and ketal formation or manipulation. It is employed in diverse organic reactions.
| Molecular weight | 106.12 |
|---|---|
| Linear formula | CH(OCH3)3 |
| Assay | 99% |
| Boiling point | 101-102 °C(lit.) |
| Density | 0.97 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.379(lit.) |
| Vapour pressure | 23.5 mmHg (20 °C)40 mmHg (30 °C)57 mmHg (40 °C) |
| Vapour density | 3.67 (vs air) |
| Application | Trimethyl orthoformate was used as dehydrating agent in the preparation of surface-modified colloidal silica nanoparticles1. |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 9 °C / 48.2 °F |
| Transport (UN / ADR) | UN 3272 3 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36 |
| Safety statements (S) | 9-16-26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trimethyl orthoformate used for?
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Trimethyl orthoformate is used as a dehydrating agent, particularly in the preparation of surface-modified colloidal silica nanoparticles, and as a building block in various chemical synthesis applications.
What are the CAS number and chemical formula for Trimethyl orthoformate?
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The CAS number for Trimethyl orthoformate is 149-73-5, and its chemical formula is CH(OCH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Trimethyl orthoformate with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should Trimethyl orthoformate be handled safely?
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Trimethyl orthoformate is highly flammable (Flash Point 9 °C) and causes serious eye irritation. Handle in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment including eyeshields, gloves, and suitable respiratory protection.
Is Trimethyl orthoformate a controlled substance?
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The provided data does not indicate that Trimethyl orthoformate is a controlled substance.
How is Trimethyl orthoformate packed and shipped?
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Trimethyl orthoformate is shipped as a flammable liquid, UN 3272, Hazard Class 3, Packing Group II.
How can I request a sample or quote for Trimethyl orthoformate?
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To request a sample or a quote for Trimethyl orthoformate, please contact the Tech Serve Solutions sales team through our website or by phone.
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