Trimethyl orthovalerate
Trimethyl orthovalerate (CAS: 13820-09-2), with the molecular formula C8H18O3 and a molecular weight of 162.23 g/mol, is a clear, colourless liquid. This orthoester is a valuable building block in organic synthesis, primarily employed for introducing the valeryl group or as a protecting agent for carbonyl compounds. Its applications extend to the preparation of complex organic molecules and pharmaceutical intermediates.
- IUPAC
- 1,1,1-Trimethoxypentane
- Synonyms
- 1,1,1-Trimethoxypentane
Synthesis of Acyl Derivatives
Trimethyl orthovalerate is utilized in the preparation of various 9-O-acyl derivatives of neuraminic acids, contributing to the synthesis of complex carbohydrates and related compounds.
Preparation of Heterocyclic Compounds
It serves as a precursor in the synthesis of diverse benzimidazolyl-quinazolinone derivatives, enabling the formation of heterocyclic ring systems.
Organic Synthesis Reagent
As an orthoester, it acts as a versatile reagent in organic synthesis, facilitating transformations such as acetalization and the introduction of ester functionalities.
| Molecular weight | 162.23 |
|---|---|
| Linear formula | CH3CH2CH2CH2C(OCH3)3 |
| Assay | 97% |
| Boiling point | 164-166 °C(lit.) |
| Density | 0.941 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.410(lit.) |
| Application | Trimethyl orthovalerate has been used in the preparation of:• various 9-O-acyl derivatives of N-acetyl- and N-glycoloyl-neuraminic acid1• 2-methyl, 2-ethyl, 2-propyl and 2-butyl-3-benzimidazolyl-4(3H)-quinazolinones2 |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 42 °C / 107.6 °F |
| Transport (UN / ADR) | UN 3272 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trimethyl orthovalerate used for?
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Trimethyl orthovalerate is used as a building block in organic synthesis, notably in the preparation of 9-O-acyl derivatives of neuraminic acids and various benzimidazolyl-quinazolinone structures.
What is the CAS number and molecular formula for Trimethyl orthovalerate?
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The CAS number is 13820-09-2 and the molecular formula is CH3CH2CH2CH2C(OCH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Trimethyl orthovalerate with a minimum assay of 97%. This product is supplied for laboratory and research use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should Trimethyl orthovalerate be handled safely?
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Trimethyl orthovalerate is a flammable liquid and vapour (H226) and can cause skin (H315) and serious eye irritation (H319). Handle with appropriate personal protective equipment including eyeshields, gloves, and use in a well-ventilated area. Refer to the Safety Data Sheet for full handling information.
Is Trimethyl orthovalerate exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Trimethyl orthovalerate, serving customers worldwide.
How can I request a quote or sample for Trimethyl orthovalerate?
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To request a quote or a sample, please use the contact form on our website or call our sales team, referencing the product name and CAS number 13820-09-2.
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