1-(Phenylsulfinyl)piperidine
1-(Phenylsulfinyl)piperidine (CAS: 4972-31-0), with the molecular formula C11H15NOS and a molecular weight of 209.31 g/mol, is a valuable heterocyclic building block. This compound serves as a selective reagent in glycosylation and mannopyranosylation reactions. It is also employed in the design of enzyme stabilizers and the synthesis of complex carbohydrate structures, including those relevant to bacterial O-antigenic polysaccharides.
- IUPAC
- 1-Benzenesulfinylpiperidine
Selective Glycosylation Reagent
1-(Phenylsulfinyl)piperidine is utilized as a reagent for selective glycosylation, enabling controlled formation of glycosidic bonds. It has also been specifically applied to mannopyranosylation, facilitating the synthesis of mannose-containing oligosaccharides.
Enzyme Stabilizer Design
This compound plays a role in the design of enzyme stabilizers. Its chemical properties allow for its incorporation into structures aimed at enhancing the stability and longevity of enzymatic activity.
Synthesis of Glycan Arrays
It is employed in the synthesis of glycan arrays for affinity studies. These arrays are crucial for investigating interactions, such as those with influenza hemagglutinins, providing insights into biological processes.
Preparation of Branched Oligosaccharides
1-(Phenylsulfinyl)piperidine is used in the preparation of orthogonal protecting groups. This facilitates the synthesis of highly branched oligosaccharides, which are complex carbohydrate structures with diverse biological functions.
Carbohydrate Synthesis
The reagent is instrumental in the synthesis of tetrasaccharide repeating units related to the O-antigenic polysaccharides of bacteria like E. coli, contributing to the study of microbial structures.
| Molecular weight | 209.31 |
|---|---|
| Empirical formula | C11H15NOS |
| Assay | 97% |
| Storage temperature | −20°C |
| Application | Reagent for:• Selective glycosylation1• Mannopyranolsylations2• Design of enzyme stabilizers3Reagent for synthesis of:• Glycan array for affinity studies with influenza hemagglutinins†• Orthogonal protecting groups for preparation of highly branched oligosaccharides4• Tetrasaccharide repeating units related to E. Coli 78 O-antigenic polysaccharides5 |
| Melting point | 84-88 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(Phenylsulfinyl)piperidine primarily used for?
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1-(Phenylsulfinyl)piperidine is primarily used as a reagent for selective glycosylation and mannopyranosylation, in the design of enzyme stabilizers, and for the synthesis of complex carbohydrate structures, including glycan arrays and oligosaccharide repeating units.
What is the CAS number and molecular formula for 1-(Phenylsulfinyl)piperidine?
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The CAS number for 1-(Phenylsulfinyl)piperidine is 4972-31-0, and its molecular formula is C11H15NOS.
What grade and purity does Tech Serve Solutions supply for 1-(Phenylsulfinyl)piperidine?
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Tech Serve Solutions supplies 1-(Phenylsulfinyl)piperidine with an assay of 97%. This product is supplied for laboratory and research use, and we do not represent it as meeting pharmacopoeial standards such as USP, BP, or EP.
How should 1-(Phenylsulfinyl)piperidine be handled safely?
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1-(Phenylsulfinyl)piperidine is classified with Warning signal word and hazard statements H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves should be worn. Ensure good ventilation and avoid breathing dust. In case of contact, rinse eyes thoroughly and wash skin with soap and water.
How is 1-(Phenylsulfinyl)piperidine typically shipped and exported?
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1-(Phenylsulfinyl)piperidine is available for purchase and export globally through Tech Serve Solutions, packaged appropriately for chemical transport.
How can I request a quote or sample for 1-(Phenylsulfinyl)piperidine?
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To request a quote or a sample of 1-(Phenylsulfinyl)piperidine, please use the contact form on the Tech Serve Solutions website or contact our sales team directly with your inquiry.
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