1-(Phenylsulfonyl)-2-indolylboronic acid MIDA ester
1-(Phenylsulfonyl)-2-indolylboronic acid MIDA ester (CAS: 1158984-95-2) is a complex organoboron compound with the molecular formula C19H17BN2O6S and a molecular weight of 412.22 g/mol. This MIDA boronate ester is primarily utilised as a versatile building block in organic synthesis. Its structure, featuring a phenylsulfonyl indole core linked to a boronic acid protected by methyliminodiacetic acid (MIDA), allows for controlled cross-coupling reactions and the construction of intricate molecular architectures.
- IUPAC
- 1-(Phenylsulfonyl)indole-2-boronic acid MIDA ester,1-(Phenylsulfonyl)indole-2-boronic acid,Methyliminodiacetic acid anhydride
Organic Synthesis Building Block
This compound serves as a key intermediate in the synthesis of complex organic molecules. The MIDA ester protection facilitates stable handling and storage while enabling selective participation in various coupling reactions.
Cross-Coupling Reactions
The boronic acid moiety, masked as a MIDA ester, is amenable to palladium-catalysed cross-coupling reactions, such as Suzuki-Miyaura couplings. This allows for the formation of new carbon-carbon bonds with high regioselectivity.
Heterocyclic Chemistry
Its indole core makes it a valuable reagent for introducing functionalised indole motifs into larger structures, relevant in medicinal chemistry and materials science research.
| Molecular weight | 412.22 |
|---|---|
| Empirical formula | C19H17BN2O6S |
| Assay | 96% |
| Application | Excludes solvent of crystallization. May contain up to 1.2 mole equivalence DMSO |
| Melting point | 159-165 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(Phenylsulfonyl)-2-indolylboronic acid MIDA ester used for?
+
1-(Phenylsulfonyl)-2-indolylboronic acid MIDA ester is primarily used as a building block in organic synthesis and for participating in cross-coupling reactions.
What is the CAS number and molecular formula for 1-(Phenylsulfonyl)-2-indolylboronic acid MIDA ester?
+
The CAS number is 1158984-95-2 and the molecular formula is C19H17BN2O6S.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound at a minimum purity of 96%. We do not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling recommendations for this product?
+
Appropriate personal protective equipment, including eyeshields and gloves, is required. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound is classified under WGK Germany 3, indicating a high hazard to water.
How is this chemical packed, shipped, and exported?
+
Tech Serve Solutions is a global supplier and exporter, capable of handling diverse packaging and shipping requirements according to international regulations.
How can I request a sample or obtain a quote for 1-(Phenylsulfonyl)-2-indolylboronic acid MIDA ester?
+
To request a sample or obtain a quote, please contact the Tech Serve Solutions sales team through our website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis